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Ube3a is required for experience-dependent maturation of the neocortex.
Yashiro K, Riday TT, Condon KH, Roberts AC, Bernardo DR, Prakash R, Weinberg RJ, Ehlers MD, Philpot BD. Yashiro K, et al. Among authors: philpot bd. Nat Neurosci. 2009 Jun;12(6):777-83. doi: 10.1038/nn.2327. Epub 2009 May 10. Nat Neurosci. 2009. PMID: 19430469 Free PMC article.
Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons.
Huang HS, Allen JA, Mabb AM, King IF, Miriyala J, Taylor-Blake B, Sciaky N, Dutton JW Jr, Lee HM, Chen X, Jin J, Bridges AS, Zylka MJ, Roth BL, Philpot BD. Huang HS, et al. Among authors: philpot bd. Nature. 2011 Dec 21;481(7380):185-9. doi: 10.1038/nature10726. Nature. 2011. PMID: 22190039 Free PMC article.
Transsynaptic signaling by activity-dependent cleavage of neuroligin-1.
Peixoto RT, Kunz PA, Kwon H, Mabb AM, Sabatini BL, Philpot BD, Ehlers MD. Peixoto RT, et al. Among authors: philpot bd. Neuron. 2012 Oct 18;76(2):396-409. doi: 10.1016/j.neuron.2012.07.006. Epub 2012 Oct 17. Neuron. 2012. PMID: 23083741 Free PMC article.
Pathway-specific dopaminergic deficits in a mouse model of Angelman syndrome.
Riday TT, Dankoski EC, Krouse MC, Fish EW, Walsh PL, Han JE, Hodge CW, Wightman RM, Philpot BD, Malanga CJ. Riday TT, et al. Among authors: philpot bd. J Clin Invest. 2012 Dec;122(12):4544-54. doi: 10.1172/JCI61888. Epub 2012 Nov 12. J Clin Invest. 2012. PMID: 23143301 Free PMC article.
Topoisomerases facilitate transcription of long genes linked to autism.
King IF, Yandava CN, Mabb AM, Hsiao JS, Huang HS, Pearson BL, Calabrese JM, Starmer J, Parker JS, Magnuson T, Chamberlain SJ, Philpot BD, Zylka MJ. King IF, et al. Among authors: philpot bd. Nature. 2013 Sep 5;501(7465):58-62. doi: 10.1038/nature12504. Epub 2013 Aug 28. Nature. 2013. PMID: 23995680 Free PMC article.
111 results