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Page 1
Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity.
Prawitt J, Abdelkarim M, Stroeve JH, Popescu I, Duez H, Velagapudi VR, Dumont J, Bouchaert E, van Dijk TH, Lucas A, Dorchies E, Daoudi M, Lestavel S, Gonzalez FJ, Oresic M, Cariou B, Kuipers F, Caron S, Staels B. Prawitt J, et al. Among authors: lucas a. Diabetes. 2011 Jul;60(7):1861-71. doi: 10.2337/db11-0030. Epub 2011 May 18. Diabetes. 2011. PMID: 21593203 Free PMC article.
The farnesoid X receptor regulates adipocyte differentiation and function by promoting peroxisome proliferator-activated receptor-gamma and interfering with the Wnt/beta-catenin pathways.
Abdelkarim M, Caron S, Duhem C, Prawitt J, Dumont J, Lucas A, Bouchaert E, Briand O, Brozek J, Kuipers F, Fievet C, Cariou B, Staels B. Abdelkarim M, et al. Among authors: lucas a. J Biol Chem. 2010 Nov 19;285(47):36759-67. doi: 10.1074/jbc.M110.166231. Epub 2010 Sep 17. J Biol Chem. 2010. PMID: 20851881 Free PMC article.
Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.
Staels B, Rubenstrunk A, Noel B, Rigou G, Delataille P, Millatt LJ, Baron M, Lucas A, Tailleux A, Hum DW, Ratziu V, Cariou B, Hanf R. Staels B, et al. Among authors: lucas a. Hepatology. 2013 Dec;58(6):1941-52. doi: 10.1002/hep.26461. Epub 2013 Oct 29. Hepatology. 2013. PMID: 23703580 Clinical Trial.
Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk.
Lien F, Berthier A, Bouchaert E, Gheeraert C, Alexandre J, Porez G, Prawitt J, Dehondt H, Ploton M, Colin S, Lucas A, Patrice A, Pattou F, Diemer H, Van Dorsselaer A, Rachez C, Kamilic J, Groen AK, Staels B, Lefebvre P. Lien F, et al. Among authors: lucas a. J Clin Invest. 2014 Mar;124(3):1037-51. doi: 10.1172/JCI68815. Epub 2014 Feb 17. J Clin Invest. 2014. PMID: 24531544 Free PMC article.
In vivo itaconate tracing reveals degradation pathway and turnover kinetics.
Willenbockel HF, Williams AT, Lucas A, Dowerg B, Cabrales P, Metallo CM, Cordes T. Willenbockel HF, et al. Among authors: lucas a. bioRxiv [Preprint]. 2025 Jan 2:2025.01.02.629617. doi: 10.1101/2025.01.02.629617. bioRxiv. 2025. PMID: 39803428 Free PMC article. Preprint.
Current Knowledge on CRISPR Strategies Against Antimicrobial-Resistant Bacteria.
de la Fuente Tagarro C, Martín-González D, De Lucas A, Bordel S, Santos-Beneit F. de la Fuente Tagarro C, et al. Among authors: de lucas a. Antibiotics (Basel). 2024 Nov 27;13(12):1141. doi: 10.3390/antibiotics13121141. Antibiotics (Basel). 2024. PMID: 39766530 Free PMC article. Review.
Microsatellite instability and high tumor mutational burden detected by next generation sequencing are concordant with loss of mismatch repair proteins by immunohistochemistry.
Yang RK, Alvarez H, Lucas AS, Roy-Chowdhuri S, Rashid A, Chen H, Ballester LY, Sweeney K, Routbort MJ, Patel KP, Luthra R, Medeiros LJ, Toruner GA. Yang RK, et al. Among authors: lucas as. Cancer Genet. 2025 Jan;290-291:44-50. doi: 10.1016/j.cancergen.2024.12.002. Epub 2024 Dec 15. Cancer Genet. 2025. PMID: 39700818
2,003 results