Haynes RK - Search Results

1

Absorption of the novel artemisinin derivatives artemisone and artemiside: potential application of Pheroid™ technology.

Steyn JD, Wiesner L, du Plessis LH, Grobler AF, Smith PJ, Chan WC, Haynes RK, Kotzé AF. Steyn JD, et al. Among authors: haynes rk. Int J Pharm. 2011 Jul 29;414(1-2):260-6. doi: 10.1016/j.ijpharm.2011.05.003. Epub 2011 May 7. Int J Pharm. 2011. PMID: 21596127

2

Interaction of artemisinins with oxyhemoglobin Hb-FeII, Hb-FeII, carboxyHb-FeII, heme-FeII, and carboxyheme FeII: significance for mode of action and implications for therapy of cerebral malaria.

Coghi P, Basilico N, Taramelli D, Chan WC, Haynes RK, Monti D. Coghi P, et al. Among authors: haynes rk. ChemMedChem. 2009 Dec;4(12):2045-53. doi: 10.1002/cmdc.200900342. ChemMedChem. 2009. PMID: 19844934

3

In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents.

Gravett AM, Liu WM, Krishna S, Chan WC, Haynes RK, Wilson NL, Dalgleish AG. Gravett AM, et al. Among authors: haynes rk. Cancer Chemother Pharmacol. 2011 Mar;67(3):569-77. doi: 10.1007/s00280-010-1355-4. Epub 2010 May 19. Cancer Chemother Pharmacol. 2011. PMID: 20490800

4

Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action.

Haynes RK, Chan WC, Wong HN, Li KY, Wu WK, Fan KM, Sung HH, Williams ID, Prosperi D, Melato S, Coghi P, Monti D. Haynes RK, et al. ChemMedChem. 2010 Aug 2;5(8):1282-99. doi: 10.1002/cmdc.201000225. ChemMedChem. 2010. PMID: 20629071

5

Artemisone effective against murine cerebral malaria.

Waknine-Grinberg JH, Hunt N, Bentura-Marciano A, McQuillan JA, Chan HW, Chan WC, Barenholz Y, Haynes RK, Golenser J. Waknine-Grinberg JH, et al. Among authors: haynes rk. Malar J. 2010 Aug 9;9:227. doi: 10.1186/1475-2875-9-227. Malar J. 2010. PMID: 20691118 Free PMC article.

6

Synthesis of artemiside and its effects in combination with conventional drugs against severe murine malaria.

Guo J, Guiguemde AW, Bentura-Marciano A, Clark J, Haynes RK, Chan WC, Wong HN, Hunt NH, Guy RK, Golenser J. Guo J, et al. Among authors: haynes rk. Antimicrob Agents Chemother. 2012 Jan;56(1):163-73. doi: 10.1128/AAC.05006-11. Epub 2011 Oct 17. Antimicrob Agents Chemother. 2012. PMID: 22006004 Free PMC article.

7

Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.

Haynes RK, Cheu KW, N'Da D, Coghi P, Monti D. Haynes RK, et al. Infect Disord Drug Targets. 2013 Aug;13(4):217-77. doi: 10.2174/1871526513666131129155708. Infect Disord Drug Targets. 2013. PMID: 24304352 Review.

8

Assessment of the induction of dormant ring stages in Plasmodium falciparum parasites by artemisone and artemisone entrapped in Pheroid vesicles in vitro.

Grobler L, Chavchich M, Haynes RK, Edstein MD, Grobler AF. Grobler L, et al. Among authors: haynes rk. Antimicrob Agents Chemother. 2014 Dec;58(12):7579-82. doi: 10.1128/AAC.02707-14. Epub 2014 Oct 6. Antimicrob Agents Chemother. 2014. PMID: 25288088 Free PMC article.

9

The Case for Development of 11-Aza-artemisinins for Malaria.

Harmse R, Wong HN, Smit F, Haynes RK, N'Da DD. Harmse R, et al. Among authors: haynes rk. Curr Med Chem. 2015;22(31):3607-30. doi: 10.2174/0929867322666150729115752. Curr Med Chem. 2015. PMID: 26219389 Review.

10

In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells.

Dwivedi A, Mazumder A, du Plessis L, du Preez JL, Haynes RK, du Plessis J. Dwivedi A, et al. Among authors: haynes rk. Nanomedicine. 2015 Nov;11(8):2041-50. doi: 10.1016/j.nano.2015.07.010. Epub 2015 Aug 15. Nanomedicine. 2015. PMID: 26282380

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