Boutin JA - Search Results

1

Structure-activity relationships of a series of analogues of the RFamide-related peptide 26RFa.

Le Marec O, Neveu C, Lefranc B, Dubessy C, Boutin JA, Do-Régo JC, Costentin J, Tonon MC, Tena-Sempere M, Vaudry H, Leprince J. Le Marec O, et al. Among authors: boutin ja. J Med Chem. 2011 Jul 14;54(13):4806-14. doi: 10.1021/jm200418c. Epub 2011 Jun 9. J Med Chem. 2011. PMID: 21623631

2

Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands.

Wallez V, Durieux-Poissonnier S, Chavatte P, Boutin JA, Audinot V, Nicolas JP, Bennejean C, Delagrange P, Renard P, Lesieur D. Wallez V, et al. Among authors: boutin ja. J Med Chem. 2002 Jun 20;45(13):2788-800. doi: 10.1021/jm0005252. J Med Chem. 2002. PMID: 12061881

3

Comment on "Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake".

Chartrel N, Alvear-Perez R, Leprince J, Iturrioz X, Reaux-Le Goazigo A, Audinot V, Chomarat P, Coge F, Nosjean O, Rodriguez M, Galizzi JP, Boutin JA, Vaudry H, Llorens-Cortes C. Chartrel N, et al. Among authors: boutin ja. Science. 2007 Feb 9;315(5813):766; author reply 766. doi: 10.1126/science.1135047. Science. 2007. PMID: 17289961

4

Design, synthesis and pharmacological evaluation of novel naphthalenic derivatives as selective MT(1) melatoninergic ligands.

Mésangeau C, Pérès B, Descamps-François C, Chavatte P, Audinot V, Coumailleau S, Boutin JA, Delagrange P, Bennejean C, Renard P, Caignard DH, Berthelot P, Yous S. Mésangeau C, et al. Among authors: boutin ja. Bioorg Med Chem. 2010 May 15;18(10):3426-36. doi: 10.1016/j.bmc.2010.04.008. Epub 2010 Apr 7. Bioorg Med Chem. 2010. PMID: 20444610

5

Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3.

Leclerc V, Ettaoussi M, Rami M, Farce A, Boutin JA, Delagrange P, Caignard DH, Renard P, Berthelot P, Yous S. Leclerc V, et al. Among authors: boutin ja. Eur J Med Chem. 2011 May;46(5):1622-9. doi: 10.1016/j.ejmech.2011.02.010. Epub 2011 Feb 15. Eur J Med Chem. 2011. PMID: 21377769

6

Preparation and pharmacological evaluation of a novel series of 2-(phenylthio)benzo[b]thiophenes as selective MT2 receptor ligands.

Mésangeau C, Fraise M, Delagrange P, Caignard DH, Boutin JA, Berthelot P, Yous S. Mésangeau C, et al. Among authors: boutin ja. Eur J Med Chem. 2011 May;46(5):1835-40. doi: 10.1016/j.ejmech.2011.02.044. Epub 2011 Feb 23. Eur J Med Chem. 2011. PMID: 21392858

7

Synthesis and pharmacological evaluation of thieno[2,3-b]pyridine derivatives as novel c-Src inhibitors.

Pevet I, Brulé C, Tizot A, Gohier A, Cruzalegui F, Boutin JA, Goldstein S. Pevet I, et al. Among authors: boutin ja. Bioorg Med Chem. 2011 Apr 15;19(8):2517-28. doi: 10.1016/j.bmc.2011.03.021. Epub 2011 Mar 13. Bioorg Med Chem. 2011. PMID: 21459579

8

Design, synthesis and pharmacological evaluation of new series of naphthalenic analogues as melatoninergic (MT1/MT2) and serotoninergic 5-HT2C dual ligands (I).

Ettaoussi M, Sabaouni A, Rami M, Boutin JA, Delagrange P, Renard P, Spedding M, Caignard DH, Berthelot P, Yous S. Ettaoussi M, et al. Among authors: boutin ja. Eur J Med Chem. 2012 Mar;49:310-23. doi: 10.1016/j.ejmech.2012.01.027. Epub 2012 Jan 20. Eur J Med Chem. 2012. PMID: 22301214

9

Rational design of a low molecular weight, stable, potent, and long-lasting GPR103 aza-β3-pseudopeptide agonist.

Neveu C, Lefranc B, Tasseau O, Do-Rego JC, Bourmaud A, Chan P, Bauchat P, Le Marec O, Chuquet J, Guilhaudis L, Boutin JA, Ségalas-Milazzo I, Costentin J, Vaudry H, Baudy-Floc'h M, Vaudry D, Leprince J. Neveu C, et al. Among authors: boutin ja. J Med Chem. 2012 Sep 13;55(17):7516-24. doi: 10.1021/jm300507d. Epub 2012 Aug 17. J Med Chem. 2012. PMID: 22800498

10

Molecular basis of agonist docking in a human GPR103 homology model by site-directed mutagenesis and structure-activity relationship studies.

Neveu C, Dulin F, Lefranc B, Galas L, Calbrix C, Bureau R, Rault S, Chuquet J, Boutin JA, Guilhaudis L, Ségalas-Milazzo I, Vaudry D, Vaudry H, Santos JS, Leprince J. Neveu C, et al. Among authors: boutin ja. Br J Pharmacol. 2014 Oct;171(19):4425-39. doi: 10.1111/bph.12808. Epub 2014 Sep 5. Br J Pharmacol. 2014. PMID: 24913445 Free PMC article.

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