Kerr WG - Search Results

1

Major remodelling of the murine stem cell kinome following differentiation in the hematopoietic compartment.

Hazen AL, Diks SH, Wahle JA, Fuhler GM, Peppelenbosch MP, Kerr WG. Hazen AL, et al. Among authors: kerr wg. J Proteome Res. 2011 Aug 5;10(8):3542-50. doi: 10.1021/pr2001594. Epub 2011 Jun 28. J Proteome Res. 2011. PMID: 21648952 Free PMC article.

2

Widespread deregulation of phosphorylation-based signaling pathways in multiple myeloma cells: opportunities for therapeutic intervention.

Fuhler GM, Diks SH, Peppelenbosch MP, Kerr WG. Fuhler GM, et al. Among authors: kerr wg. Mol Med. 2011;17(7-8):790-8. doi: 10.2119/molmed.2011.00013. Epub 2011 Apr 28. Mol Med. 2011. PMID: 21541441 Free PMC article.

3

Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation.

Hoekstra E, Das AM, Willemsen M, Swets M, Kuppen PJ, van der Woude CJ, Bruno MJ, Shah JP, Ten Hagen TL, Chisholm JD, Kerr WG, Peppelenbosch MP, Fuhler GM. Hoekstra E, et al. Among authors: kerr wg. Oncotarget. 2016 Nov 8;7(45):73525-73540. doi: 10.18632/oncotarget.12321. Oncotarget. 2016. PMID: 27716613 Free PMC article.

4

Analysis of SHIP1 expression and activity in Crohn's disease patients.

Somasundaram R, Fernandes S, Deuring JJ, de Haar C, Kuipers EJ, Vogelaar L, Middleton FA, van der Woude CJ, Peppelenbosch MP, Kerr WG, Fuhler GM. Somasundaram R, et al. Among authors: kerr wg. PLoS One. 2017 Aug 2;12(8):e0182308. doi: 10.1371/journal.pone.0182308. eCollection 2017. PLoS One. 2017. PMID: 28767696 Free PMC article.

5

SHIP is required for a functional hematopoietic stem cell niche.

Hazen AL, Smith MJ, Desponts C, Winter O, Moser K, Kerr WG. Hazen AL, et al. Among authors: kerr wg. Blood. 2009 Mar 26;113(13):2924-33. doi: 10.1182/blood-2008-02-138008. Epub 2008 Dec 12. Blood. 2009. PMID: 19074735 Free PMC article.

6

SHIP deficiency enhances HSC proliferation and survival but compromises homing and repopulation.

Desponts C, Hazen AL, Paraiso KH, Kerr WG. Desponts C, et al. Among authors: kerr wg. Blood. 2006 Jun 1;107(11):4338-45. doi: 10.1182/blood-2005-12-5021. Epub 2006 Feb 7. Blood. 2006. PMID: 16467196 Free PMC article.

7

Lineage extrinsic and intrinsic control of immunoregulatory cell numbers by SHIP.

Collazo MM, Paraiso KH, Park MY, Hazen AL, Kerr WG. Collazo MM, et al. Among authors: kerr wg. Eur J Immunol. 2012 Jul;42(7):1785-95. doi: 10.1002/eji.201142092. Eur J Immunol. 2012. PMID: 22535653 Free PMC article.

8

Cutting edge: dominance by an MHC-independent inhibitory receptor compromises NK killing of complex targets.

Wahle JA, Paraiso KH, Costello AL, Goll EL, Sentman CL, Kerr WG. Wahle JA, et al. Among authors: kerr wg. J Immunol. 2006 Jun 15;176(12):7165-9. doi: 10.4049/jimmunol.176.12.7165. J Immunol. 2006. PMID: 16751359

9

Inappropriate recruitment and activity by the Src homology region 2 domain-containing phosphatase 1 (SHP1) is responsible for receptor dominance in the SHIP-deficient NK cell.

Wahle JA, Paraiso KH, Kendig RD, Lawrence HR, Chen L, Wu J, Kerr WG. Wahle JA, et al. Among authors: kerr wg. J Immunol. 2007 Dec 15;179(12):8009-15. doi: 10.4049/jimmunol.179.12.8009. J Immunol. 2007. PMID: 18056340

10

SHIP1 inhibition increases immunoregulatory capacity and triggers apoptosis of hematopoietic cancer cells.

Brooks R, Fuhler GM, Iyer S, Smith MJ, Park MY, Paraiso KH, Engelman RW, Kerr WG. Brooks R, et al. Among authors: kerr wg. J Immunol. 2010 Apr 1;184(7):3582-9. doi: 10.4049/jimmunol.0902844. Epub 2010 Mar 3. J Immunol. 2010. PMID: 20200281 Free PMC article.

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