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Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication.
Boeckemeier L, Kraehenbuehl R, Keszthelyi A, Gasasira MU, Vernon EG, Beardmore R, Vågbø CB, Chaplin D, Gollins S, Krokan HE, Lambert SAE, Paizs B, Hartsuiker E. Boeckemeier L, et al. Among authors: hartsuiker e. Sci Adv. 2020 May 29;6(22):eaaz4126. doi: 10.1126/sciadv.aaz4126. eCollection 2020 May. Sci Adv. 2020. PMID: 32523988 Free PMC article.
Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair.
Nakamura K, Kogame T, Oshiumi H, Shinohara A, Sumitomo Y, Agama K, Pommier Y, Tsutsui KM, Tsutsui K, Hartsuiker E, Ogi T, Takeda S, Taniguchi Y. Nakamura K, et al. Among authors: hartsuiker e. PLoS Genet. 2010 Jan 22;6(1):e1000828. doi: 10.1371/journal.pgen.1000828. PLoS Genet. 2010. PMID: 20107609 Free PMC article.
28 results