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Tamoxifen inhibits inward rectifier K+ 2.x family of inward rectifier channels by interfering with phosphatidylinositol 4,5-bisphosphate-channel interactions.
Ponce-Balbuena D, López-Izquierdo A, Ferrer T, Rodríguez-Menchaca AA, Aréchiga-Figueroa IA, Sánchez-Chapula JA. Ponce-Balbuena D, et al. Among authors: ferrer t. J Pharmacol Exp Ther. 2009 Nov;331(2):563-73. doi: 10.1124/jpet.109.156075. Epub 2009 Aug 4. J Pharmacol Exp Ther. 2009. PMID: 19654266
The antimalarial drug mefloquine inhibits cardiac inward rectifier K+ channels: evidence for interference in PIP2-channel interaction.
López-Izquierdo A, Ponce-Balbuena D, Moreno-Galindo EG, Aréchiga-Figueroa IA, Rodríguez-Martínez M, Ferrer T, Rodríguez-Menchaca AA, Sánchez-Chapula JA. López-Izquierdo A, et al. Among authors: ferrer t. J Cardiovasc Pharmacol. 2011 Apr;57(4):407-15. doi: 10.1097/FJC.0b013e31820b7c03. J Cardiovasc Pharmacol. 2011. PMID: 21502926
Molecular genetic and functional association of Brugada and early repolarization syndromes with S422L missense mutation in KCNJ8.
Barajas-Martínez H, Hu D, Ferrer T, Onetti CG, Wu Y, Burashnikov E, Boyle M, Surman T, Urrutia J, Veltmann C, Schimpf R, Borggrefe M, Wolpert C, Ibrahim BB, Sánchez-Chapula JA, Winters S, Haïssaguerre M, Antzelevitch C. Barajas-Martínez H, et al. Among authors: ferrer t. Heart Rhythm. 2012 Apr;9(4):548-55. doi: 10.1016/j.hrthm.2011.10.035. Epub 2011 Nov 3. Heart Rhythm. 2012. PMID: 22056721 Free PMC article.
78 results