Medema MH - Search Results

1

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences.

Medema MH, Blin K, Cimermancic P, de Jager V, Zakrzewski P, Fischbach MA, Weber T, Takano E, Breitling R. Medema MH, et al. Nucleic Acids Res. 2011 Jul;39(Web Server issue):W339-46. doi: 10.1093/nar/gkr466. Epub 2011 Jun 14. Nucleic Acids Res. 2011. PMID: 21672958 Free PMC article.

2

Empowering natural product science with AI: leveraging multimodal data and knowledge graphs.

Meijer D, Beniddir MA, Coley CW, Mejri YM, Öztürk M, van der Hooft JJJ, Medema MH, Skiredj A. Meijer D, et al. Among authors: medema mh. Nat Prod Rep. 2024 Aug 16. doi: 10.1039/d4np00008k. Online ahead of print. Nat Prod Rep. 2024. PMID: 39148455 Free PMC article. Review.

3

Total Synthesis and Structure Assignment of the Relacidine Lipopeptide Antibiotics and Preparation of Analogues with Enhanced Stability.

Al Ayed K, Zamarbide Losada D, Machushynets NV, Terlouw B, Elsayed SS, Schill J, Trebosc V, Pieren M, Medema MH, van Wezel GP, Martin NI. Al Ayed K, et al. Among authors: medema mh. ACS Infect Dis. 2023 Apr 14;9(4):739-748. doi: 10.1021/acsinfecdis.3c00043. Epub 2023 Mar 31. ACS Infect Dis. 2023. PMID: 37000899 Free PMC article.

4

bacLIFE: a user-friendly computational workflow for genome analysis and prediction of lifestyle-associated genes in bacteria.

Guerrero-Egido G, Pintado A, Bretscher KM, Arias-Giraldo LM, Paulson JN, Spaink HP, Claessen D, Ramos C, Cazorla FM, Medema MH, Raaijmakers JM, Carrión VJ. Guerrero-Egido G, et al. Among authors: medema mh. Nat Commun. 2024 Mar 7;15(1):2072. doi: 10.1038/s41467-024-46302-y. Nat Commun. 2024. PMID: 38453959 Free PMC article.

5

TbasCO: trait-based comparative 'omics identifies ecosystem-level and niche-differentiating adaptations of an engineered microbiome.

McDaniel EA, van Steenbrugge JJM, Noguera DR, McMahon KD, Raaijmakers JM, Medema MH, Oyserman BO. McDaniel EA, et al. Among authors: medema mh. ISME Commun. 2022 Nov 7;2(1):111. doi: 10.1038/s43705-022-00189-2. ISME Commun. 2022. PMID: 37938301 Free PMC article.

6

Exploring the Interspecific Interactions and the Metabolome of the Soil Isolate Hylemonella gracilis.

Tyc O, Kulkarni P, Ossowicki A, Tracanna V, Medema MH, van Baarlen P, van IJcken WFJ, Verhoeven KJF, Garbeva P. Tyc O, et al. Among authors: medema mh. mSystems. 2023 Feb 23;8(1):e0057422. doi: 10.1128/msystems.00574-22. Epub 2022 Dec 20. mSystems. 2023. PMID: 36537799 Free PMC article.

7

The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.

Medema MH, Trefzer A, Kovalchuk A, van den Berg M, Müller U, Heijne W, Wu L, Alam MT, Ronning CM, Nierman WC, Bovenberg RA, Breitling R, Takano E. Medema MH, et al. Genome Biol Evol. 2010 Jul 12;2:212-24. doi: 10.1093/gbe/evq013. Genome Biol Evol. 2010. PMID: 20624727 Free PMC article.

8

Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms.

Medema MH, Breitling R, Bovenberg R, Takano E. Medema MH, et al. Nat Rev Microbiol. 2011 Feb;9(2):131-7. doi: 10.1038/nrmicro2478. Epub 2010 Dec 29. Nat Rev Microbiol. 2011. PMID: 21189477 Review.

9

Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus.

Medema MH, Alam MT, Heijne WH, van den Berg MA, Müller U, Trefzer A, Bovenberg RA, Breitling R, Takano E. Medema MH, et al. Microb Biotechnol. 2011 Mar;4(2):300-5. doi: 10.1111/j.1751-7915.2010.00226.x. Epub 2010 Nov 2. Microb Biotechnol. 2011. PMID: 21342474 Free PMC article.

10

NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity.

Röttig M, Medema MH, Blin K, Weber T, Rausch C, Kohlbacher O. Röttig M, et al. Among authors: medema mh. Nucleic Acids Res. 2011 Jul;39(Web Server issue):W362-7. doi: 10.1093/nar/gkr323. Epub 2011 May 9. Nucleic Acids Res. 2011. PMID: 21558170 Free PMC article.

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