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Page 1
Mass spectrometric identification of novel lysine acetylation sites in huntingtin.
Cong X, Held JM, DeGiacomo F, Bonner A, Chen JM, Schilling B, Czerwieniec GA, Gibson BW, Ellerby LM. Cong X, et al. Among authors: degiacomo f. Mol Cell Proteomics. 2011 Oct;10(10):M111.009829. doi: 10.1074/mcp.M111.009829. Epub 2011 Jun 18. Mol Cell Proteomics. 2011. PMID: 21685499 Free PMC article.
Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.
O'Brien R, DeGiacomo F, Holcomb J, Bonner A, Ring KL, Zhang N, Zafar K, Weiss A, Lager B, Schilling B, Gibson BW, Chen S, Kwak S, Ellerby LM. O'Brien R, et al. Among authors: degiacomo f. J Biol Chem. 2015 Jul 31;290(31):19287-306. doi: 10.1074/jbc.M114.623561. Epub 2015 May 29. J Biol Chem. 2015. PMID: 26025364 Free PMC article.
Caspase-6 activity in a BACHD mouse modulates steady-state levels of mutant huntingtin protein but is not necessary for production of a 586 amino acid proteolytic fragment.
Gafni J, Papanikolaou T, Degiacomo F, Holcomb J, Chen S, Menalled L, Kudwa A, Fitzpatrick J, Miller S, Ramboz S, Tuunanen PI, Lehtimäki KK, Yang XW, Park L, Kwak S, Howland D, Park H, Ellerby LM. Gafni J, et al. Among authors: degiacomo f. J Neurosci. 2012 May 30;32(22):7454-65. doi: 10.1523/JNEUROSCI.6379-11.2012. J Neurosci. 2012. PMID: 22649225 Free PMC article.
A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease.
Miller JP, Yates BE, Al-Ramahi I, Berman AE, Sanhueza M, Kim E, de Haro M, DeGiacomo F, Torcassi C, Holcomb J, Gafni J, Mooney SD, Botas J, Ellerby LM, Hughes RE. Miller JP, et al. Among authors: degiacomo f. PLoS Genet. 2012;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29. PLoS Genet. 2012. PMID: 23209424 Free PMC article.