El-Deiry WS - Search Results

1

Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents.

Wang W, Gallant JN, Katz SI, Dolloff NG, Smith CD, Abdulghani J, Allen JE, Dicker DT, Hong B, Navaraj A, El-Deiry WS. Wang W, et al. Cancer Biol Ther. 2011 Aug 1;12(3):229-38. doi: 10.4161/cbt.12.3.17033. Epub 2011 Aug 1. Cancer Biol Ther. 2011. PMID: 21725212 Free article.

2

Homozygous deletion of the death receptor DR4 gene in a nasopharyngeal cancer cell line is associated with TRAIL resistance.

Ozören N, Fisher MJ, Kim K, Liu CX, Genin A, Shifman Y, Dicker DT, Spinner NB, Lisitsyn NA, El-Deiry WS. Ozören N, et al. Int J Oncol. 2000 May;16(5):917-25. doi: 10.3892/ijo.16.5.917. Int J Oncol. 2000. PMID: 10762627

3

Repression of BRCA1 through a feedback loop involving p53.

MacLachlan TK, Dash BC, Dicker DT, El-Deiry WS. MacLachlan TK, et al. J Biol Chem. 2000 Oct 13;275(41):31869-75. doi: 10.1074/jbc.M003338200. J Biol Chem. 2000. PMID: 10884389 Free article.

4

The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.

Ozoren N, Kim K, Burns TF, Dicker DT, Moscioni AD, El-Deiry WS. Ozoren N, et al. Cancer Res. 2000 Nov 15;60(22):6259-65. Cancer Res. 2000. PMID: 11103780

5

Bax is a transcriptional target and mediator of c-myc-induced apoptosis.

Mitchell KO, Ricci MS, Miyashita T, Dicker DT, Jin Z, Reed JC, El-Deiry WS. Mitchell KO, et al. Cancer Res. 2000 Nov 15;60(22):6318-25. Cancer Res. 2000. PMID: 11103792

6

Enhanced TRAIL sensitivity by p53 overexpression in human cancer but not normal cell lines.

Kim K, Takimoto R, Dicker DT, Chen Y, Gazitt Y, El-Deiry WS. Kim K, et al. Int J Oncol. 2001 Feb;18(2):241-7. doi: 10.3892/ijo.18.2.241. Int J Oncol. 2001. PMID: 11172588

7

Death domain mutagenesis of KILLER/DR5 reveals residues critical for apoptotic signaling.

McDonald ER 3rd, Chui PC, Martelli PF, Dicker DT, El-Deiry WS. McDonald ER 3rd, et al. J Biol Chem. 2001 May 4;276(18):14939-45. doi: 10.1074/jbc.M100399200. Epub 2001 Feb 13. J Biol Chem. 2001. PMID: 11279061 Free article.

8

BRCA1 transcriptionally regulates damaged DNA binding protein (DDB2) in the DNA repair response following UV-irradiation.

Takimoto R, MacLachlan TK, Dicker DT, Niitsu Y, Mori T, el-Deiry WS. Takimoto R, et al. Cancer Biol Ther. 2002 Mar-Apr;1(2):177-86. doi: 10.4161/cbt.65. Cancer Biol Ther. 2002. PMID: 12170778 Free article.

9

The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein.

Takimoto R, Wang W, Dicker DT, Rastinejad F, Lyssikatos J, el-Deiry WS. Takimoto R, et al. Cancer Biol Ther. 2002 Jan-Feb;1(1):47-55. doi: 10.4161/cbt.1.1.41. Cancer Biol Ther. 2002. PMID: 12174820 Free article.

10

Enhanced sensitivity of G1 arrested human cancer cells suggests a novel therapeutic strategy using a combination of simvastatin and TRAIL.

Jin Z, Dicker DT, El-Deiry WS. Jin Z, et al. Cell Cycle. 2002 Jan;1(1):82-9. Cell Cycle. 2002. PMID: 12429913

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