Ditzler MA - Search Results

1

Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates.

Ditzler MA, Bose D, Shkriabai N, Marchand B, Sarafianos SG, Kvaratskhelia M, Burke DH. Ditzler MA, et al. Nucleic Acids Res. 2011 Oct;39(18):8237-47. doi: 10.1093/nar/gkr381. Epub 2011 Jul 3. Nucleic Acids Res. 2011. PMID: 21727088 Free PMC article.

2

High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase.

Ditzler MA, Lange MJ, Bose D, Bottoms CA, Virkler KF, Sawyer AW, Whatley AS, Spollen W, Givan SA, Burke DH. Ditzler MA, et al. Nucleic Acids Res. 2013 Feb 1;41(3):1873-84. doi: 10.1093/nar/gks1190. Epub 2012 Dec 14. Nucleic Acids Res. 2013. PMID: 23241386 Free PMC article.

3

Potent Inhibition of HIV-1 Reverse Transcriptase and Replication by Nonpseudoknot, "UCAA-motif" RNA Aptamers.

Whatley AS, Ditzler MA, Lange MJ, Biondi E, Sawyer AW, Chang JL, Franken JD, Burke DH. Whatley AS, et al. Among authors: ditzler ma. Mol Ther Nucleic Acids. 2013 Feb 5;2(2):e71. doi: 10.1038/mtna.2012.62. Mol Ther Nucleic Acids. 2013. PMID: 23385524 Free PMC article.

4

A rugged free energy landscape separates multiple functional RNA folds throughout denaturation.

Ditzler MA, Rueda D, Mo J, Håkansson K, Walter NG. Ditzler MA, et al. Nucleic Acids Res. 2008 Dec;36(22):7088-99. doi: 10.1093/nar/gkn871. Epub 2008 Nov 6. Nucleic Acids Res. 2008. PMID: 18988629 Free PMC article.

5

Selection of 2'-Deoxy-2'-Fluoroarabino Nucleic Acid (FANA) Aptamers That Bind HIV-1 Integrase with Picomolar Affinity.

Rose KM, Alves Ferreira-Bravo I, Li M, Craigie R, Ditzler MA, Holliger P, DeStefano JJ. Rose KM, et al. Among authors: ditzler ma. ACS Chem Biol. 2019 Oct 18;14(10):2166-2175. doi: 10.1021/acschembio.9b00237. Epub 2019 Oct 7. ACS Chem Biol. 2019. PMID: 31560515 Free PMC article.

6

In vitro selections with RNAs of variable length converge on a robust catalytic core.

Popović M, Ellingson AQ, Chu TP, Wei C, Pohorille A, Ditzler MA. Popović M, et al. Among authors: ditzler ma. Nucleic Acids Res. 2021 Jan 25;49(2):674-683. doi: 10.1093/nar/gkaa1238. Nucleic Acids Res. 2021. PMID: 33367725 Free PMC article.

7

In vitro evolution of distinct self-cleaving ribozymes in diverse environments.

Popović M, Fliss PS, Ditzler MA. Popović M, et al. Among authors: ditzler ma. Nucleic Acids Res. 2015 Aug 18;43(14):7070-82. doi: 10.1093/nar/gkv648. Epub 2015 Jun 29. Nucleic Acids Res. 2015. PMID: 26130717 Free PMC article.

8

Focus on function: single molecule RNA enzymology.

Ditzler MA, Alemán EA, Rueda D, Walter NG. Ditzler MA, et al. Biopolymers. 2007 Dec 5-15;87(5-6):302-16. doi: 10.1002/bip.20819. Biopolymers. 2007. PMID: 17685395 Free article. Review.

9

Molecular dynamics suggest multifunctionality of an adenine imino group in acid-base catalysis of the hairpin ribozyme.

Ditzler MA, Sponer J, Walter NG. Ditzler MA, et al. RNA. 2009 Apr;15(4):560-75. doi: 10.1261/rna.1416709. Epub 2009 Feb 17. RNA. 2009. PMID: 19223444 Free PMC article.

10

Molecular dynamics and quantum mechanics of RNA: conformational and chemical change we can believe in.

Ditzler MA, Otyepka M, Sponer J, Walter NG. Ditzler MA, et al. Acc Chem Res. 2010 Jan 19;43(1):40-7. doi: 10.1021/ar900093g. Acc Chem Res. 2010. PMID: 19754142 Free PMC article.

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