Smith DM - Search Results

1

Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry.

Deriziotis P, André R, Smith DM, Goold R, Kinghorn KJ, Kristiansen M, Nathan JA, Rosenzweig R, Krutauz D, Glickman MH, Collinge J, Goldberg AL, Tabrizi SJ. Deriziotis P, et al. Among authors: smith dm. EMBO J. 2011 Jul 8;30(15):3065-77. doi: 10.1038/emboj.2011.224. EMBO J. 2011. PMID: 21743439 Free PMC article.

2

Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.

Yu Y, Smith DM, Kim HM, Rodriguez V, Goldberg AL, Cheng Y. Yu Y, et al. Among authors: smith dm. EMBO J. 2010 Feb 3;29(3):692-702. doi: 10.1038/emboj.2009.382. Epub 2009 Dec 17. EMBO J. 2010. PMID: 20019667 Free PMC article.

3

Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry.

Smith DM, Chang SC, Park S, Finley D, Cheng Y, Goldberg AL. Smith DM, et al. Mol Cell. 2007 Sep 7;27(5):731-44. doi: 10.1016/j.molcel.2007.06.033. Mol Cell. 2007. PMID: 17803938 Free PMC article.

4

Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases.

Rabl J, Smith DM, Yu Y, Chang SC, Goldberg AL, Cheng Y. Rabl J, et al. Among authors: smith dm. Mol Cell. 2008 May 9;30(3):360-8. doi: 10.1016/j.molcel.2008.03.004. Mol Cell. 2008. PMID: 18471981 Free PMC article.

5

ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins.

Smith DM, Kafri G, Cheng Y, Ng D, Walz T, Goldberg AL. Smith DM, et al. Mol Cell. 2005 Dec 9;20(5):687-98. doi: 10.1016/j.molcel.2005.10.019. Mol Cell. 2005. PMID: 16337593 Free article.

6

Proteasomes and their associated ATPases: a destructive combination.

Smith DM, Benaroudj N, Goldberg A. Smith DM, et al. J Struct Biol. 2006 Oct;156(1):72-83. doi: 10.1016/j.jsb.2006.04.012. Epub 2006 May 8. J Struct Biol. 2006. PMID: 16919475 Review.

7

ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle.

Smith DM, Fraga H, Reis C, Kafri G, Goldberg AL. Smith DM, et al. Cell. 2011 Feb 18;144(4):526-38. doi: 10.1016/j.cell.2011.02.005. Cell. 2011. PMID: 21335235 Free PMC article.

8

ATP-induced structural transitions in PAN, the proteasome-regulatory ATPase complex in Archaea.

Horwitz AA, Navon A, Groll M, Smith DM, Reis C, Goldberg AL. Horwitz AA, et al. Among authors: smith dm. J Biol Chem. 2007 Aug 3;282(31):22921-9. doi: 10.1074/jbc.M702846200. Epub 2007 Jun 6. J Biol Chem. 2007. PMID: 17553803 Free article.

9

Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism.

Dange T, Smith D, Noy T, Rommel PC, Jurzitza L, Cordero RJ, Legendre A, Finley D, Goldberg AL, Schmidt M. Dange T, et al. J Biol Chem. 2011 Dec 16;286(50):42830-9. doi: 10.1074/jbc.M111.300178. Epub 2011 Oct 24. J Biol Chem. 2011. PMID: 22025621 Free PMC article.

10

A conserved F box regulatory complex controls proteasome activity in Drosophila.

Bader M, Benjamin S, Wapinski OL, Smith DM, Goldberg AL, Steller H. Bader M, et al. Among authors: smith dm. Cell. 2011 Apr 29;145(3):371-82. doi: 10.1016/j.cell.2011.03.021. Cell. 2011. PMID: 21529711 Free PMC article.

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