Youssef S - Search Results

1

1,25-dihydroxyvitamin D(3) ameliorates Th17 autoimmunity via transcriptional modulation of interleukin-17A.

Joshi S, Pantalena LC, Liu XK, Gaffen SL, Liu H, Rohowsky-Kochan C, Ichiyama K, Yoshimura A, Steinman L, Christakos S, Youssef S. Joshi S, et al. Among authors: youssef s. Mol Cell Biol. 2011 Sep;31(17):3653-69. doi: 10.1128/MCB.05020-11. Epub 2011 Jul 11. Mol Cell Biol. 2011. PMID: 21746882 Free PMC article.

2

At once harmful and beneficial: the dual properties of NF-kappaB.

Youssef S, Steinman L. Youssef S, et al. Nat Immunol. 2006 Sep;7(9):901-2. doi: 10.1038/ni0906-901. Nat Immunol. 2006. PMID: 16924250 No abstract available.

3

Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity.

Platten M, Youssef S, Hur EM, Ho PP, Han MH, Lanz TV, Phillips LK, Goldstein MJ, Bhat R, Raine CS, Sobel RA, Steinman L. Platten M, et al. Among authors: youssef s. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14948-53. doi: 10.1073/pnas.0903958106. Epub 2009 Aug 19. Proc Natl Acad Sci U S A. 2009. PMID: 19706421 Free PMC article.

4

Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin.

Dunn SE, Youssef S, Goldstein MJ, Prod'homme T, Weber MS, Zamvil SS, Steinman L. Dunn SE, et al. Among authors: youssef s. J Exp Med. 2006 Feb 20;203(2):401-12. doi: 10.1084/jem.20051129. Epub 2006 Feb 13. J Exp Med. 2006. PMID: 16476765 Free PMC article.

5

Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity.

Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. Dunn SE, et al. Among authors: youssef s. J Exp Med. 2007 Feb 19;204(2):321-30. doi: 10.1084/jem.20061839. Epub 2007 Jan 29. J Exp Med. 2007. PMID: 17261635 Free PMC article.

6

Neither T-helper type 2 nor Foxp3+ regulatory T cells are necessary for therapeutic benefit of atorvastatin in treatment of central nervous system autoimmunity.

Weber MS, Prod'homme T, Youssef S, Dunn SE, Steinman L, Zamvil SS. Weber MS, et al. Among authors: youssef s. J Neuroinflammation. 2014 Feb 6;11:29. doi: 10.1186/1742-2094-11-29. J Neuroinflammation. 2014. PMID: 24498870 Free PMC article.

7

The potential therapeutic role of statins in central nervous system autoimmune disorders.

Stüve O, Youssef S, Dunn S, Slavin AJ, Steinman L, Zamvil SS. Stüve O, et al. Among authors: youssef s. Cell Mol Life Sci. 2003 Nov;60(11):2483-91. doi: 10.1007/s00018-003-3146-0. Cell Mol Life Sci. 2003. PMID: 14625690 Free PMC article. Review.

8

Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells.

Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, Steinman L. Hur EM, et al. Among authors: youssef s. Nat Immunol. 2007 Jan;8(1):74-83. doi: 10.1038/ni1415. Epub 2006 Dec 3. Nat Immunol. 2007. PMID: 17143274

9

NAD⁺ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity.

Meyer T, Shimon D, Youssef S, Yankovitz G, Tessler A, Chernobylsky T, Gaoni-Yogev A, Perelroizen R, Budick-Harmelin N, Steinman L, Mayo L. Meyer T, et al. Among authors: youssef s. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2211310119. doi: 10.1073/pnas.2211310119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994674 Free PMC article.

10

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease.

Youssef S, Stüve O, Patarroyo JC, Ruiz PJ, Radosevich JL, Hur EM, Bravo M, Mitchell DJ, Sobel RA, Steinman L, Zamvil SS. Youssef S, et al. Nature. 2002 Nov 7;420(6911):78-84. doi: 10.1038/nature01158. Nature. 2002. PMID: 12422218

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