Backx PH - Search Results

1

Iron overload decreases CaV1.3-dependent L-type Ca2+ currents leading to bradycardia, altered electrical conduction, and atrial fibrillation.

Rose RA, Sellan M, Simpson JA, Izaddoustdar F, Cifelli C, Panama BK, Davis M, Zhao D, Markhani M, Murphy GG, Striessnig J, Liu PP, Heximer SP, Backx PH. Rose RA, et al. Among authors: backx ph. Circ Arrhythm Electrophysiol. 2011 Oct;4(5):733-42. doi: 10.1161/CIRCEP.110.960401. Epub 2011 Jul 11. Circ Arrhythm Electrophysiol. 2011. PMID: 21747058 Free PMC article.

2

Relationship between K+ channel down-regulation and [Ca2+]i in rat ventricular myocytes following myocardial infarction.

Kaprielian R, Wickenden AD, Kassiri Z, Parker TG, Liu PP, Backx PH. Kaprielian R, et al. Among authors: backx ph. J Physiol. 1999 May 15;517 ( Pt 1)(Pt 1):229-45. doi: 10.1111/j.1469-7793.1999.0229z.x. J Physiol. 1999. PMID: 10226162 Free PMC article.

3

Modulation of iron uptake in heart by L-type Ca2+ channel modifiers: possible implications in iron overload.

Tsushima RG, Wickenden AD, Bouchard RA, Oudit GY, Liu PP, Backx PH. Tsushima RG, et al. Among authors: backx ph. Circ Res. 1999 Jun 11;84(11):1302-9. doi: 10.1161/01.res.84.11.1302. Circ Res. 1999. PMID: 10364568

4

Cardiac function and cytotoxic aldehyde production in a murine model of chronic iron-overload.

Bartfay WJ, Dawood F, Wen WH, Lehotay DC, Hou D, Bartfay E, Luo X, Backx PH, Liu PP. Bartfay WJ, et al. Among authors: backx ph. Cardiovasc Res. 1999 Sep;43(4):892-900. doi: 10.1016/s0008-6363(99)00040-1. Cardiovasc Res. 1999. PMID: 10615416

5

Cytotoxic aldehyde generation in heart following acute iron-loading.

Bartfay WJ, Hou D, Lehotay DC, Luo X, Bartfay E, Backx PH, Liu PP. Bartfay WJ, et al. Among authors: backx ph. J Trace Elem Med Biol. 2000 Apr;14(1):14-20. doi: 10.1016/S0946-672X(00)80018-8. J Trace Elem Med Biol. 2000. PMID: 10836529

6

Inhibition of calcineurin and sarcolemmal Ca2+ influx protects cardiac morphology and ventricular function in K(v)4.2N transgenic mice.

Sah R, Oudit GY, Nguyen TT, Lim HW, Wickenden AD, Wilson GJ, Molkentin JD, Backx PH. Sah R, et al. Among authors: backx ph. Circulation. 2002 Apr 16;105(15):1850-6. doi: 10.1161/01.cir.0000014211.47830.4d. Circulation. 2002. PMID: 11956130

7

Prevention of hypertrophy by overexpression of Kv4.2 in cultured neonatal cardiomyocytes.

Zobel C, Kassiri Z, Nguyen TT, Meng Y, Backx PH. Zobel C, et al. Among authors: backx ph. Circulation. 2002 Oct 29;106(18):2385-91. doi: 10.1161/01.cir.0000033970.22130.93. Circulation. 2002. PMID: 12403671

8

L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy.

Oudit GY, Sun H, Trivieri MG, Koch SE, Dawood F, Ackerley C, Yazdanpanah M, Wilson GJ, Schwartz A, Liu PP, Backx PH. Oudit GY, et al. Among authors: backx ph. Nat Med. 2003 Sep;9(9):1187-94. doi: 10.1038/nm920. Epub 2003 Aug 24. Nat Med. 2003. PMID: 12937413

9

Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure.

Oudit GY, Crackower MA, Eriksson U, Sarao R, Kozieradzki I, Sasaki T, Irie-Sasaki J, Gidrewicz D, Rybin VO, Wada T, Steinberg SF, Backx PH, Penninger JM. Oudit GY, et al. Among authors: backx ph. Circulation. 2003 Oct 28;108(17):2147-52. doi: 10.1161/01.CIR.0000091403.62293.2B. Epub 2003 Sep 8. Circulation. 2003. PMID: 12963636

10

Taurine supplementation reduces oxidative stress and improves cardiovascular function in an iron-overload murine model.

Oudit GY, Trivieri MG, Khaper N, Husain T, Wilson GJ, Liu P, Sole MJ, Backx PH. Oudit GY, et al. Among authors: backx ph. Circulation. 2004 Apr 20;109(15):1877-85. doi: 10.1161/01.CIR.0000124229.40424.80. Epub 2004 Mar 22. Circulation. 2004. PMID: 15037530

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