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Oxidative stress modulates heme synthesis and induces peroxiredoxin-2 as a novel cytoprotective response in β-thalassemic erythropoiesis.
De Franceschi L, Bertoldi M, De Falco L, Santos Franco S, Ronzoni L, Turrini F, Colancecco A, Camaschella C, Cappellini MD, Iolascon A. De Franceschi L, et al. Among authors: de falco l. Haematologica. 2011 Nov;96(11):1595-604. doi: 10.3324/haematol.2011.043612. Epub 2011 Jul 12. Haematologica. 2011. PMID: 21750082 Free PMC article. Clinical Trial.
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice.
Franco SS, De Falco L, Ghaffari S, Brugnara C, Sinclair DA, Matte' A, Iolascon A, Mohandas N, Bertoldi M, An X, Siciliano A, Rimmelé P, Cappellini MD, Michan S, Zoratti E, Anne J, De Franceschi L. Franco SS, et al. Among authors: de franceschi l, de falco l. Haematologica. 2014 Feb;99(2):267-75. doi: 10.3324/haematol.2013.090076. Epub 2013 Aug 23. Haematologica. 2014. PMID: 23975182 Free PMC article. Clinical Trial.
The Interplay Between Peroxiredoxin-2 and Nuclear Factor-Erythroid 2 Is Important in Limiting Oxidative Mediated Dysfunction in β-Thalassemic Erythropoiesis.
Matte A, De Falco L, Iolascon A, Mohandas N, An X, Siciliano A, Leboeuf C, Janin A, Bruno M, Choi SY, Kim DW, De Franceschi L. Matte A, et al. Among authors: de franceschi l, de falco l. Antioxid Redox Signal. 2015 Dec 1;23(16):1284-97. doi: 10.1089/ars.2014.6237. Epub 2015 Jul 14. Antioxid Redox Signal. 2015. PMID: 26058667 Free PMC article.
How I Diagnose Non-thalassemic Microcytic Anemias.
Bruno M, De Falco L, Iolascon A. Bruno M, et al. Among authors: de falco l. Semin Hematol. 2015 Oct;52(4):270-8. doi: 10.1053/j.seminhematol.2015.05.002. Epub 2015 Jun 3. Semin Hematol. 2015. PMID: 26404439 Review.
Iron refractory iron deficiency anemia.
De Falco L, Sanchez M, Silvestri L, Kannengiesser C, Muckenthaler MU, Iolascon A, Gouya L, Camaschella C, Beaumont C. De Falco L, et al. Haematologica. 2013 Jun;98(6):845-53. doi: 10.3324/haematol.2012.075515. Haematologica. 2013. PMID: 23729726 Free PMC article. Review.
Peroxiredoxin-2: A Novel Regulator of Iron Homeostasis in Ineffective Erythropoiesis.
Matte A, De Falco L, Federti E, Cozzi A, Iolascon A, Levi S, Mohandas N, Zamo A, Bruno M, Lebouef C, Janin A, Siciliano A, Ganz T, Federico G, Carlomagno F, Mueller S, Silva I, Carbone C, Melisi D, Kim DW, Choi SY, De Franceschi L. Matte A, et al. Among authors: de franceschi l, de falco l. Antioxid Redox Signal. 2018 Jan 1;28(1):1-14. doi: 10.1089/ars.2017.7051. Epub 2017 Sep 6. Antioxid Redox Signal. 2018. PMID: 28793778
Fyn kinase is a novel modulator of erythropoietin signaling and stress erythropoiesis.
Beneduce E, Matte A, De Falco L, Mbiandjeu S, Chiabrando D, Tolosano E, Federti E, Petrillo S, Mohandas N, Siciliano A, Babu W, Menon V, Ghaffari S, Iolascon A, De Franceschi L. Beneduce E, et al. Among authors: de franceschi l, de falco l. Am J Hematol. 2019 Jan;94(1):10-20. doi: 10.1002/ajh.25295. Epub 2018 Oct 25. Am J Hematol. 2019. PMID: 30252956 Free PMC article.
Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of β-thalassemia.
Matte A, Federti E, Winter M, Koerner A, Harmeier A, Mazer N, Tomka T, Di Paolo ML, De Falco L, Andolfo I, Beneduce E, Iolascon A, Macias-Garcia A, Chen JJ, Janin A, Lebouef C, Turrini F, Brugnara C, De Franceschi L. Matte A, et al. Among authors: de franceschi l, de falco l. JCI Insight. 2019 Nov 14;4(22):e130111. doi: 10.1172/jci.insight.130111. JCI Insight. 2019. PMID: 31593554 Free PMC article.
67 results