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The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation.
Wang L, Gural A, Sun XJ, Zhao X, Perna F, Huang G, Hatlen MA, Vu L, Liu F, Xu H, Asai T, Xu H, Deblasio T, Menendez S, Voza F, Jiang Y, Cole PA, Zhang J, Melnick A, Roeder RG, Nimer SD. Wang L, et al. Among authors: nimer sd. Science. 2011 Aug 5;333(6043):765-9. doi: 10.1126/science.1201662. Epub 2011 Jul 14. Science. 2011. PMID: 21764752 Free PMC article.
The AML1/ETO fusion protein activates transcription of BCL-2.
Klampfer L, Zhang J, Zelenetz AO, Uchida H, Nimer SD. Klampfer L, et al. Among authors: nimer sd. Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14059-64. doi: 10.1073/pnas.93.24.14059. Proc Natl Acad Sci U S A. 1996. PMID: 8943060 Free PMC article.
284 results