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Graft-versus-leukemia (GVL) against mouse blast-crisis chronic myelogenous leukemia (BC-CML) and chronic-phase chronic myelogenous leukemia (CP-CML): shared mechanisms of T cell killing, but programmed death ligands render CP-CML and not BC-CML GVL resistant.
Matte-Martone C, Venkatesan S, Tan HS, Athanasiadis I, Chang J, Pavisic J, Shlomchik WD. Matte-Martone C, et al. Among authors: shlomchik wd. J Immunol. 2011 Aug 15;187(4):1653-63. doi: 10.4049/jimmunol.1100311. Epub 2011 Jul 18. J Immunol. 2011. PMID: 21768400 Free PMC article.
Donor APCs are required for maximal GVHD but not for GVL.
Matte CC, Liu J, Cormier J, Anderson BE, Athanasiadis I, Jain D, McNiff J, Shlomchik WD. Matte CC, et al. Among authors: shlomchik wd. Nat Med. 2004 Sep;10(9):987-92. doi: 10.1038/nm1089. Epub 2004 Aug 1. Nat Med. 2004. PMID: 15286785 Free article.
Target antigens determine graft-versus-host disease phenotype.
Kaplan DH, Anderson BE, McNiff JM, Jain D, Shlomchik MJ, Shlomchik WD. Kaplan DH, et al. Among authors: shlomchik mj, shlomchik wd. J Immunol. 2004 Nov 1;173(9):5467-75. doi: 10.4049/jimmunol.173.9.5467. J Immunol. 2004. PMID: 15494494
Graft-versus-host disease.
Shlomchik WD. Shlomchik WD. Nat Rev Immunol. 2007 May;7(5):340-52. doi: 10.1038/nri2000. Nat Rev Immunol. 2007. PMID: 17438575 Review.
GVL against murine chronic phase and blast phase CML.
Shlomchik W. Shlomchik W. Biol Blood Marrow Transplant. 2008 Jan;14(1 Suppl 1):4. doi: 10.1016/j.bbmt.2007.10.005. Biol Blood Marrow Transplant. 2008. PMID: 18162213 Free article. No abstract available.
72 results