Yang JY - Search Results

1

RasGAP-derived fragment N increases the resistance of beta cells towards apoptosis in NOD mice and delays the progression from mild to overt diabetes.

Bulat N, Jaccard E, Peltzer N, Khalil H, Yang JY, Dubuis G, Widmann C. Bulat N, et al. Among authors: yang jy. PLoS One. 2011;6(7):e22609. doi: 10.1371/journal.pone.0022609. Epub 2011 Jul 25. PLoS One. 2011. PMID: 21799917 Free PMC article.

2

The RasGAP N-terminal fragment generated by caspase cleavage protects cells in a Ras/PI3K/Akt-dependent manner that does not rely on NFkappa B activation.

Yang JY, Widmann C. Yang JY, et al. J Biol Chem. 2002 Apr 26;277(17):14641-6. doi: 10.1074/jbc.M111540200. Epub 2002 Feb 14. J Biol Chem. 2002. PMID: 11847220 Free article.

3

Impaired Akt activity down-modulation, caspase-3 activation, and apoptosis in cells expressing a caspase-resistant mutant of RasGAP at position 157.

Yang JY, Walicki J, Michod D, Dubuis G, Widmann C. Yang JY, et al. Mol Biol Cell. 2005 Aug;16(8):3511-20. doi: 10.1091/mbc.e05-01-0080. Epub 2005 May 18. Mol Biol Cell. 2005. PMID: 15901831 Free PMC article.

4

Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop.

Cornu M, Yang JY, Jaccard E, Poussin C, Widmann C, Thorens B. Cornu M, et al. Among authors: yang jy. Diabetes. 2009 Aug;58(8):1816-25. doi: 10.2337/db09-0063. Epub 2009 Apr 28. Diabetes. 2009. PMID: 19401425 Free PMC article.

5

Expression of the NH(2)-terminal fragment of RasGAP in pancreatic beta-cells increases their resistance to stresses and protects mice from diabetes.

Yang JY, Walicki J, Jaccard E, Dubuis G, Bulat N, Hornung JP, Thorens B, Widmann C. Yang JY, et al. Diabetes. 2009 Nov;58(11):2596-606. doi: 10.2337/db09-0104. Epub 2009 Aug 20. Diabetes. 2009. PMID: 19696184 Free PMC article.

6

Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell Protection.

Peltzer N, Vanli G, Yang JY, Widmann C. Peltzer N, et al. Among authors: yang jy. PLoS One. 2013 Jun 27;8(6):e68123. doi: 10.1371/journal.pone.0068123. Print 2013. PLoS One. 2013. PMID: 23826368 Free PMC article.

7

Surviving the kiss of death.

Yang JY, Michod D, Walicki J, Widmann C. Yang JY, et al. Biochem Pharmacol. 2004 Sep 15;68(6):1027-31. doi: 10.1016/j.bcp.2004.03.043. Biochem Pharmacol. 2004. PMID: 15313397 Review.

8

A RasGAP-derived cell permeable peptide potently enhances genotoxin-induced cytotoxicity in tumor cells.

Michod D, Yang JY, Chen J, Bonny C, Widmann C. Michod D, et al. Among authors: yang jy. Oncogene. 2004 Nov 25;23(55):8971-8. doi: 10.1038/sj.onc.1207999. Oncogene. 2004. PMID: 15467750

9

Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions.

Yang JY, Michod D, Walicki J, Murphy BM, Kasibhatla S, Martin SJ, Widmann C. Yang JY, et al. Mol Cell Biol. 2004 Dec;24(23):10425-36. doi: 10.1128/MCB.24.23.10425-10436.2004. Mol Cell Biol. 2004. PMID: 15542850 Free PMC article.

10

Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion.

Yang JY, Walicki J, Abderrahmani A, Cornu M, Waeber G, Thorens B, Widmann C. Yang JY, et al. J Biol Chem. 2005 Sep 23;280(38):32835-42. doi: 10.1074/jbc.M504058200. Epub 2005 Jul 25. J Biol Chem. 2005. PMID: 16046410 Free article.

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