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Page 1
Regulation of TFEB and V-ATPases by mTORC1.
Peña-Llopis S, Vega-Rubin-de-Celis S, Schwartz JC, Wolff NC, Tran TA, Zou L, Xie XJ, Corey DR, Brugarolas J. Peña-Llopis S, et al. Among authors: wolff nc. EMBO J. 2011 Jul 29;30(16):3242-58. doi: 10.1038/emboj.2011.257. EMBO J. 2011. PMID: 21804531 Free PMC article.
Interplay between pVHL and mTORC1 pathways in clear-cell renal cell carcinoma.
Kucejova B, Peña-Llopis S, Yamasaki T, Sivanand S, Tran TA, Alexander S, Wolff NC, Lotan Y, Xie XJ, Kabbani W, Kapur P, Brugarolas J. Kucejova B, et al. Among authors: wolff nc. Mol Cancer Res. 2011 Sep;9(9):1255-65. doi: 10.1158/1541-7786.MCR-11-0302. Epub 2011 Jul 28. Mol Cancer Res. 2011. PMID: 21798997 Free PMC article.
A validated tumorgraft model reveals activity of dovitinib against renal cell carcinoma.
Sivanand S, Peña-Llopis S, Zhao H, Kucejova B, Spence P, Pavia-Jimenez A, Yamasaki T, McBride DJ, Gillen J, Wolff NC, Morlock L, Lotan Y, Raj GV, Sagalowsky A, Margulis V, Cadeddu JA, Ross MT, Bentley DR, Kabbani W, Xie XJ, Kapur P, Williams NS, Brugarolas J. Sivanand S, et al. Among authors: wolff nc. Sci Transl Med. 2012 Jun 6;4(137):137ra75. doi: 10.1126/scitranslmed.3003643. Sci Transl Med. 2012. PMID: 22674553 Free PMC article.
Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis.
Wang SS, Gu YF, Wolff N, Stefanius K, Christie A, Dey A, Hammer RE, Xie XJ, Rakheja D, Pedrosa I, Carroll T, McKay RM, Kapur P, Brugarolas J. Wang SS, et al. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16538-43. doi: 10.1073/pnas.1414789111. Epub 2014 Oct 30. Proc Natl Acad Sci U S A. 2014. PMID: 25359211 Free PMC article.
Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade.
Gu YF, Cohn S, Christie A, McKenzie T, Wolff N, Do QN, Madhuranthakam AJ, Pedrosa I, Wang T, Dey A, Busslinger M, Xie XJ, Hammer RE, McKay RM, Kapur P, Brugarolas J. Gu YF, et al. Cancer Discov. 2017 Aug;7(8):900-917. doi: 10.1158/2159-8290.CD-17-0292. Epub 2017 May 4. Cancer Discov. 2017. PMID: 28473526 Free PMC article.
Sirolimus and temsirolimus for epithelioid angiomyolipoma.
Wolff N, Kabbani W, Bradley T, Raj G, Watumull L, Brugarolas J. Wolff N, et al. J Clin Oncol. 2010 Feb 10;28(5):e65-8. doi: 10.1200/JCO.2009.26.3061. Epub 2010 Jan 4. J Clin Oncol. 2010. PMID: 20048172 No abstract available.
17 results