Mewett KN - Search Results

1

Flavan-3-ol esters: new agents for exploring modulatory sites on GABA(A) receptors.

Fernandez SP, Karim N, Mewett KN, Chebib M, Johnston GA, Hanrahan JR. Fernandez SP, et al. Among authors: mewett kn. Br J Pharmacol. 2012 Feb;165(4):965-77. doi: 10.1111/j.1476-5381.2011.01615.x. Br J Pharmacol. 2012. PMID: 21806603 Free PMC article.

2

trans-4-Amino-2-methylbut-2-enoic acid (2-MeTACA) and (+/-)-trans-2-aminomethylcyclopropanecarboxylic acid ((+/-)-TAMP) can differentiate rat rho3 from human rho1 and rho2 recombinant GABA(C) receptors.

Vien J, Duke RK, Mewett KN, Johnston GA, Shingai R, Chebib M. Vien J, et al. Among authors: mewett kn. Br J Pharmacol. 2002 Feb;135(4):883-90. doi: 10.1038/sj.bjp.0704432. Br J Pharmacol. 2002. PMID: 11861315 Free PMC article.

3

Convulsant actions of calycanthine.

Chebib M, Duke RK, Duke CC, Connor M, Mewett KN, Johnston GA. Chebib M, et al. Among authors: mewett kn. Toxicol Appl Pharmacol. 2003 Jul 1;190(1):58-64. doi: 10.1016/s0041-008x(03)00149-2. Toxicol Appl Pharmacol. 2003. PMID: 12831783

4

GABA(C) receptors as drug targets.

Johnston GA, Chebib M, Hanrahan JR, Mewett KN. Johnston GA, et al. Among authors: mewett kn. Curr Drug Targets CNS Neurol Disord. 2003 Aug;2(4):260-8. doi: 10.2174/1568007033482805. Curr Drug Targets CNS Neurol Disord. 2003. PMID: 12871036 Review.

5

Mutations of the 2' proline in the M2 domain of the human GABAC rho1 subunit alter agonist responses.

Carland JE, Moore AM, Hanrahan JR, Mewett KN, Duke RK, Johnston GA, Chebib M. Carland JE, et al. Among authors: mewett kn. Neuropharmacology. 2004 May;46(6):770-81. doi: 10.1016/j.neuropharm.2003.11.027. Neuropharmacology. 2004. PMID: 15033337

6

(3-Aminocyclopentyl)methylphosphinic acids: novel GABA(C) receptor antagonists.

Chebib M, Hanrahan JR, Kumar RJ, Mewett KN, Morriss G, Wooller S, Johnston GA. Chebib M, et al. Among authors: mewett kn. Neuropharmacology. 2007 Mar;52(3):779-87. doi: 10.1016/j.neuropharm.2006.09.014. Epub 2006 Nov 13. Neuropharmacology. 2007. PMID: 17098260

7

Modulation of ionotropic GABA receptors by natural products of plant origin.

Johnston GA, Hanrahan JR, Chebib M, Duke RK, Mewett KN. Johnston GA, et al. Among authors: mewett kn. Adv Pharmacol. 2006;54:285-316. doi: 10.1016/s1054-3589(06)54012-8. Adv Pharmacol. 2006. PMID: 17175819 Review. No abstract available.

8

Flavan-3-ol derivatives are positive modulators of GABA(A) receptors with higher efficacy for the alpha(2) subtype and anxiolytic action in mice.

Fernandez SP, Mewett KN, Hanrahan JR, Chebib M, Johnston GA. Fernandez SP, et al. Among authors: mewett kn. Neuropharmacology. 2008 Oct;55(5):900-7. doi: 10.1016/j.neuropharm.2008.06.069. Epub 2008 Jul 9. Neuropharmacology. 2008. PMID: 18657554

9

Guanidino acids act as rho1 GABA(C) receptor antagonists.

Chebib M, Gavande N, Wong KY, Park A, Premoli I, Mewett KN, Allan RD, Duke RK, Johnston GA, Hanrahan JR. Chebib M, et al. Among authors: mewett kn. Neurochem Res. 2009 Oct;34(10):1704-11. doi: 10.1007/s11064-009-9968-x. Epub 2009 Apr 23. Neurochem Res. 2009. PMID: 19387831

10

Synthesis and biological evaluation of flavan-3-ol derivatives as positive modulators of GABAA receptors.

Mewett KN, Fernandez SP, Pasricha AK, Pong A, Devenish SO, Hibbs DE, Chebib M, Johnston GA, Hanrahan JR. Mewett KN, et al. Bioorg Med Chem. 2009 Oct 15;17(20):7156-73. doi: 10.1016/j.bmc.2009.08.062. Epub 2009 Sep 4. Bioorg Med Chem. 2009. PMID: 19783443

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