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Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network.
Zhang SS, Kim KH, Rosen A, Smyth JW, Sakuma R, Delgado-Olguín P, Davis M, Chi NC, Puviindran V, Gaborit N, Sukonnik T, Wylie JN, Brand-Arzamendi K, Farman GP, Kim J, Rose RA, Marsden PA, Zhu Y, Zhou YQ, Miquerol L, Henkelman RM, Stainier DY, Shaw RM, Hui CC, Bruneau BG, Backx PH. Zhang SS, et al. Among authors: rose ra. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13576-81. doi: 10.1073/pnas.1106911108. Epub 2011 Aug 8. Proc Natl Acad Sci U S A. 2011. PMID: 21825130 Free PMC article.
Iron overload decreases CaV1.3-dependent L-type Ca2+ currents leading to bradycardia, altered electrical conduction, and atrial fibrillation.
Rose RA, Sellan M, Simpson JA, Izaddoustdar F, Cifelli C, Panama BK, Davis M, Zhao D, Markhani M, Murphy GG, Striessnig J, Liu PP, Heximer SP, Backx PH. Rose RA, et al. Circ Arrhythm Electrophysiol. 2011 Oct;4(5):733-42. doi: 10.1161/CIRCEP.110.960401. Epub 2011 Jul 11. Circ Arrhythm Electrophysiol. 2011. PMID: 21747058 Free PMC article.
Loss of insulin signaling may contribute to atrial fibrillation and atrial electrical remodeling in type 1 diabetes.
Polina I, Jansen HJ, Li T, Moghtadaei M, Bohne LJ, Liu Y, Krishnaswamy P, Egom EE, Belke DD, Rafferty SA, Ezeani M, Gillis AM, Rose RA. Polina I, et al. Among authors: rose ra. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7990-8000. doi: 10.1073/pnas.1914853117. Epub 2020 Mar 20. Proc Natl Acad Sci U S A. 2020. PMID: 32198206 Free PMC article.
156 results