Robinson PJ - Search Results

1

Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism.

Harper CB, Martin S, Nguyen TH, Daniels SJ, Lavidis NA, Popoff MR, Hadzic G, Mariana A, Chau N, McCluskey A, Robinson PJ, Meunier FA. Harper CB, et al. Among authors: robinson pj. J Biol Chem. 2011 Oct 14;286(41):35966-35976. doi: 10.1074/jbc.M111.283879. Epub 2011 Aug 5. J Biol Chem. 2011. PMID: 21832053 Free PMC article.

2

Dynamin I is a Ca(2+)-sensitive phospholipid-binding protein with very high affinity for protein kinase C.

Liu JP, Powell KA, Südhof TC, Robinson PJ. Liu JP, et al. Among authors: robinson pj. J Biol Chem. 1994 Aug 19;269(33):21043-50. J Biol Chem. 1994. PMID: 8063723 Free article.

3

Ca(2+) influx inhibits dynamin and arrests synaptic vesicle endocytosis at the active zone.

Cousin MA, Robinson PJ. Cousin MA, et al. Among authors: robinson pj. J Neurosci. 2000 Feb 1;20(3):949-57. doi: 10.1523/JNEUROSCI.20-03-00949.2000. J Neurosci. 2000. PMID: 10648699 Free PMC article.

4

Phosphorylation of dynamin I on Ser-795 by protein kinase C blocks its association with phospholipids.

Powell KA, Valova VA, Malladi CS, Jensen ON, Larsen MR, Robinson PJ. Powell KA, et al. Among authors: robinson pj. J Biol Chem. 2000 Apr 21;275(16):11610-7. doi: 10.1074/jbc.275.16.11610. J Biol Chem. 2000. PMID: 10766777 Free article.

5

Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity.

Hill TA, Odell LR, Quan A, Abagyan R, Ferguson G, Robinson PJ, McCluskey A. Hill TA, et al. Among authors: robinson pj. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3275-8. doi: 10.1016/j.bmcl.2004.03.096. Bioorg Med Chem Lett. 2004. PMID: 15149689

6

Small molecule inhibitors of dynamin I GTPase activity: development of dimeric tyrphostins.

Hill T, Odell LR, Edwards JK, Graham ME, McGeachie AB, Rusak J, Quan A, Abagyan R, Scott JL, Robinson PJ, McCluskey A. Hill T, et al. Among authors: robinson pj. J Med Chem. 2005 Dec 1;48(24):7781-8. doi: 10.1021/jm040208l. J Med Chem. 2005. PMID: 16302817

7

The in vivo phosphorylation sites of rat brain dynamin I.

Graham ME, Anggono V, Bache N, Larsen MR, Craft GE, Robinson PJ. Graham ME, et al. Among authors: robinson pj. J Biol Chem. 2007 May 18;282(20):14695-707. doi: 10.1074/jbc.M609713200. Epub 2007 Mar 20. J Biol Chem. 2007. PMID: 17376771 Free article.

8

Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II.

Quan A, McGeachie AB, Keating DJ, van Dam EM, Rusak J, Chau N, Malladi CS, Chen C, McCluskey A, Cousin MA, Robinson PJ. Quan A, et al. Among authors: robinson pj. Mol Pharmacol. 2007 Dec;72(6):1425-39. doi: 10.1124/mol.107.034207. Epub 2007 Aug 16. Mol Pharmacol. 2007. PMID: 17702890

9

Steroids from an Australian sponge Psammoclema sp.

Holland IP, McCluskey A, Sakoff JA, Gilbert J, Chau N, Robinson PJ, Motti CA, Wright AD, van Altena IA. Holland IP, et al. Among authors: robinson pj. J Nat Prod. 2009 Jan;72(1):102-6. doi: 10.1021/np800688f. J Nat Prod. 2009. PMID: 19132863

10

Azido and diazarinyl analogues of bis-tyrphostin as asymmetrical inhibitors of dynamin GTPase.

Odell LR, Chau N, Mariana A, Graham ME, Robinson PJ, McCluskey A. Odell LR, et al. Among authors: robinson pj. ChemMedChem. 2009 Jul;4(7):1182-8. doi: 10.1002/cmdc.200900054. ChemMedChem. 2009. PMID: 19437476

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