Diener C - Search Results

1

CTEP: a novel, potent, long-acting, and orally bioavailable metabotropic glutamate receptor 5 inhibitor.

Lindemann L, Jaeschke G, Michalon A, Vieira E, Honer M, Spooren W, Porter R, Hartung T, Kolczewski S, Büttelmann B, Flament C, Diener C, Fischer C, Gatti S, Prinssen EP, Parrott N, Hoffmann G, Wettstein JG. Lindemann L, et al. Among authors: diener c. J Pharmacol Exp Ther. 2011 Nov;339(2):474-86. doi: 10.1124/jpet.111.185660. Epub 2011 Aug 17. J Pharmacol Exp Ther. 2011. PMID: 21849627

2

Mutational analysis and molecular modeling of the binding pocket of the metabotropic glutamate 5 receptor negative modulator 2-methyl-6-(phenylethynyl)-pyridine.

Malherbe P, Kratochwil N, Zenner MT, Piussi J, Diener C, Kratzeisen C, Fischer C, Porter RH. Malherbe P, et al. Among authors: diener c. Mol Pharmacol. 2003 Oct;64(4):823-32. doi: 10.1124/mol.64.4.823. Mol Pharmacol. 2003. PMID: 14500738

3

Constitutive activity modulation of human metabotropic glutamate 5a receptors in HEK293 cells: a role for key amino-terminal cysteine residues.

Mühlemann A, Diener C, Fischer C, Piussi J, Stucki A, Porter RH. Mühlemann A, et al. Among authors: diener c. Br J Pharmacol. 2005 Apr;144(8):1118-25. doi: 10.1038/sj.bjp.0706152. Br J Pharmacol. 2005. PMID: 15700023 Free PMC article.

4

Determination of key amino acids implicated in the actions of allosteric modulation by 3,3'-difluorobenzaldazine on rat mGlu5 receptors.

Mühlemann A, Ward NA, Kratochwil N, Diener C, Fischer C, Stucki A, Jaeschke G, Malherbe P, Porter RH. Mühlemann A, et al. Among authors: diener c. Eur J Pharmacol. 2006 Jan 4;529(1-3):95-104. doi: 10.1016/j.ejphar.2005.11.008. Epub 2005 Dec 13. Eur J Pharmacol. 2006. PMID: 16352303

5

Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors.

Werthmann RC, Tzouros M, Lamerz J, Augustin A, Fritzius T, Trovò L, Stawarski M, Raveh A, Diener C, Fischer C, Gassmann M, Lindemann L, Bettler B. Werthmann RC, et al. Among authors: diener c. Neuropharmacology. 2021 Jun 1;190:108426. doi: 10.1016/j.neuropharm.2020.108426. Epub 2020 Dec 3. Neuropharmacology. 2021. PMID: 33279506 Free article.

6

cDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein.

Malherbe P, Richards JG, Gaillard H, Thompson A, Diener C, Schuler A, Huber G. Malherbe P, et al. Among authors: diener c. Brain Res Mol Brain Res. 1999 Aug 25;71(2):159-70. doi: 10.1016/s0169-328x(99)00174-6. Brain Res Mol Brain Res. 1999. PMID: 10521570

7

Metagenomic estimation of absolute bacterial biomass in the mammalian gut through host-derived read normalization.

Tang G, Carr AV, Perez C, Ramos Sarmiento K, Levy L, Lampe JW, Diener C, Gibbons SM. Tang G, et al. Among authors: diener c. bioRxiv [Preprint]. 2025 Jan 7:2025.01.07.631807. doi: 10.1101/2025.01.07.631807. bioRxiv. 2025. PMID: 39829744 Free PMC article. Preprint.

8

Expanding the immune-related targetome of miR-155-5p by integrating time-resolved RNA patterns into miRNA target prediction.

Hart M, Diener C, Rheinheimer S, Kehl T, Keller A, Lenhof HP, Meese E. Hart M, et al. Among authors: diener c. RNA Biol. 2025 Dec;22(1):1-9. doi: 10.1080/15476286.2025.2449775. Epub 2025 Jan 11. RNA Biol. 2025. PMID: 39760255 Free PMC article. Review.

9

Neonates exposed to HIV but uninfected exhibit an altered gut microbiota and inflammation associated with impaired breast milk antibody function.

Byrne A, Diener C, Brown BP, Maust BS, Feng C, Alinde BL, Gibbons SM, Koch M, Gray CM, Jaspan HB, Nyangahu DD. Byrne A, et al. Among authors: diener c. Microbiome. 2024 Dec 20;12(1):261. doi: 10.1186/s40168-024-01973-z. Microbiome. 2024. PMID: 39707483 Free PMC article.

10

Understanding disease-associated metabolic changes in human colon epithelial cells using i ColonEpithelium metabolic reconstruction.

Jiang B, Quinn-Bohmann N, Diener C, Nathan VB, Han-Hallett Y, Reddivari L, Gibbons SM, Baloni P. Jiang B, et al. Among authors: diener c. bioRxiv [Preprint]. 2024 Oct 25:2024.10.22.619644. doi: 10.1101/2024.10.22.619644. bioRxiv. 2024. PMID: 39484551 Free PMC article. Preprint.

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