Perumal M - Search Results

1

Targeting somatostatin receptors: preclinical evaluation of novel 18F-fluoroethyltriazole-Tyr3-octreotate analogs for PET.

Leyton J, Iddon L, Perumal M, Indrevoll B, Glaser M, Robins E, George AJ, Cuthbertson A, Luthra SK, Aboagye EO. Leyton J, et al. Among authors: perumal m. J Nucl Med. 2011 Sep;52(9):1441-8. doi: 10.2967/jnumed.111.088906. Epub 2011 Aug 18. J Nucl Med. 2011. PMID: 21852355 Free article.

2

Radiosynthesis and pre-clinical evaluation of [(18)F]fluoro-[1,2-(2)H(4)]choline.

Smith G, Zhao Y, Leyton J, Shan B, Nguyen QD, Perumal M, Turton D, Årstad E, Luthra SK, Robins EG, Aboagye EO. Smith G, et al. Among authors: perumal m. Nucl Med Biol. 2011 Jan;38(1):39-51. doi: 10.1016/j.nucmedbio.2010.06.012. Epub 2010 Sep 1. Nucl Med Biol. 2011. PMID: 21220128

3

The uptake of 3'-deoxy-3'-[18F]fluorothymidine into L5178Y tumours in vivo is dependent on thymidine kinase 1 protein levels.

Barthel H, Perumal M, Latigo J, He Q, Brady F, Luthra SK, Price PM, Aboagye EO. Barthel H, et al. Among authors: perumal m. Eur J Nucl Med Mol Imaging. 2005 Mar;32(3):257-63. doi: 10.1007/s00259-004-1611-0. Epub 2004 Sep 4. Eur J Nucl Med Mol Imaging. 2005. PMID: 15791434

4

Early detection of tumor response to chemotherapy by 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography: the effect of cisplatin on a fibrosarcoma tumor model in vivo.

Leyton J, Latigo JR, Perumal M, Dhaliwal H, He Q, Aboagye EO. Leyton J, et al. Among authors: perumal m. Cancer Res. 2005 May 15;65(10):4202-10. doi: 10.1158/0008-5472.CAN-04-4008. Cancer Res. 2005. PMID: 15899811

5

In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography.

Leyton J, Alao JP, Da Costa M, Stavropoulou AV, Latigo JR, Perumal M, Pillai R, He Q, Atadja P, Lam EW, Workman P, Vigushin DM, Aboagye EO. Leyton J, et al. Among authors: perumal m. Cancer Res. 2006 Aug 1;66(15):7621-9. doi: 10.1158/0008-5472.CAN-05-3962. Cancer Res. 2006. PMID: 16885362

6

Imaging pharmacodynamics of the alpha-folate receptor-targeted thymidylate synthase inhibitor BGC 945.

Pillai RG, Forster M, Perumal M, Mitchell F, Leyton J, Aibgirhio FI, Golovko O, Jackman AL, Aboagye EO. Pillai RG, et al. Among authors: perumal m. Cancer Res. 2008 May 15;68(10):3827-34. doi: 10.1158/0008-5472.CAN-08-0135. Cancer Res. 2008. PMID: 18483267 Free PMC article.

7

Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901.

Leyton J, Smith G, Lees M, Perumal M, Nguyen QD, Aigbirhio FI, Golovko O, He Q, Workman P, Aboagye EO. Leyton J, et al. Among authors: perumal m. Mol Cancer Ther. 2008 Sep;7(9):3112-21. doi: 10.1158/1535-7163.MCT-08-0264. Mol Cancer Ther. 2008. PMID: 18790789

8

Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F]fluoroethylazide.

Smith G, Glaser M, Perumal M, Nguyen QD, Shan B, Arstad E, Aboagye EO. Smith G, et al. Among authors: perumal m. J Med Chem. 2008 Dec 25;51(24):8057-67. doi: 10.1021/jm801107u. J Med Chem. 2008. PMID: 19049429

9

[18F]fluoromethyl-[1,2-2H4]-choline: a novel radiotracer for imaging choline metabolism in tumors by positron emission tomography.

Leyton J, Smith G, Zhao Y, Perumal M, Nguyen QD, Robins E, Arstad E, Aboagye EO. Leyton J, et al. Among authors: perumal m. Cancer Res. 2009 Oct 1;69(19):7721-8. doi: 10.1158/0008-5472.CAN-09-1419. Epub 2009 Sep 22. Cancer Res. 2009. PMID: 19773436 Free PMC article.

10

Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide.

Nguyen QD, Smith G, Glaser M, Perumal M, Arstad E, Aboagye EO. Nguyen QD, et al. Among authors: perumal m. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16375-80. doi: 10.1073/pnas.0901310106. Epub 2009 Sep 3. Proc Natl Acad Sci U S A. 2009. PMID: 19805307 Free PMC article.

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