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Sphingomyelin synthase 1-generated sphingomyelin plays an important role in transferrin trafficking and cell proliferation.
Shakor ABA, Taniguchi M, Kitatani K, Hashimoto M, Asano S, Hayashi A, Nomura K, Bielawski J, Bielawska A, Watanabe K, Kobayashi T, Igarashi Y, Umehara H, Takeya H, Okazaki T. Shakor ABA, et al. Among authors: igarashi y. J Biol Chem. 2011 Oct 14;286(41):36053-36062. doi: 10.1074/jbc.M111.228593. Epub 2011 Aug 19. J Biol Chem. 2011. PMID: 21856749 Free PMC article.
Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes.
Mitsutake S, Zama K, Yokota H, Yoshida T, Tanaka M, Mitsui M, Ikawa M, Okabe M, Tanaka Y, Yamashita T, Takemoto H, Okazaki T, Watanabe K, Igarashi Y. Mitsutake S, et al. Among authors: igarashi y. J Biol Chem. 2011 Aug 12;286(32):28544-55. doi: 10.1074/jbc.M111.255646. Epub 2011 Jun 13. J Biol Chem. 2011. PMID: 21669879 Free PMC article.
Regulation of autophagy and its associated cell death by "sphingolipid rheostat": reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway.
Taniguchi M, Kitatani K, Kondo T, Hashimoto-Nishimura M, Asano S, Hayashi A, Mitsutake S, Igarashi Y, Umehara H, Takeya H, Kigawa J, Okazaki T. Taniguchi M, et al. Among authors: igarashi y. J Biol Chem. 2012 Nov 16;287(47):39898-910. doi: 10.1074/jbc.M112.416552. Epub 2012 Oct 3. J Biol Chem. 2012. PMID: 23035115 Free PMC article.
Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway.
Asano S, Kitatani K, Taniguchi M, Hashimoto M, Zama K, Mitsutake S, Igarashi Y, Takeya H, Kigawa J, Hayashi A, Umehara H, Okazaki T. Asano S, et al. Among authors: igarashi y. Mol Cell Biol. 2012 Aug;32(16):3242-52. doi: 10.1128/MCB.00121-12. Epub 2012 Jun 11. Mol Cell Biol. 2012. PMID: 22688512 Free PMC article.
2,201 results