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Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients.
Kasher PR, De Vos KJ, Wharton SB, Manser C, Bennett EJ, Bingley M, Wood JD, Milner R, McDermott CJ, Miller CC, Shaw PJ, Grierson AJ. Kasher PR, et al. Among authors: bennett ej. J Neurochem. 2009 Jul;110(1):34-44. doi: 10.1111/j.1471-4159.2009.06104.x. Epub 2009 Apr 22. J Neurochem. 2009. PMID: 19453301 Free article.
No evidence for cardiac dysfunction in Kif6 mutant mice.
Hameed A, Bennett E, Ciani B, Hoebers LP, Milner R, Lawrie A, Francis SE, Grierson AJ. Hameed A, et al. PLoS One. 2013;8(1):e54636. doi: 10.1371/journal.pone.0054636. Epub 2013 Jan 23. PLoS One. 2013. PMID: 23355886 Free PMC article.
S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis.
Mead RJ, Higginbottom A, Allen SP, Kirby J, Bennett E, Barber SC, Heath PR, Coluccia A, Patel N, Gardner I, Brancale A, Grierson AJ, Shaw PJ. Mead RJ, et al. Free Radic Biol Med. 2013 Aug;61:438-52. doi: 10.1016/j.freeradbiomed.2013.04.018. Epub 2013 Apr 19. Free Radic Biol Med. 2013. PMID: 23608463 Free PMC article.
Increased CXCL10 (IP-10) is associated with advanced myeloproliferative neoplasms and its loss dampens erythrocytosis in mouse models.
Belmonte M, Cabrera-Cosme L, Øbro NF, Li J, Grinfeld J, Milek J, Bennett E, Irvine M, Shepherd MS, Cull AH, Boyd G, Riedel LM, Chi Che JL, Oedekoven CA, Baxter EJ, Green AR, Barlow JL, Kent DG. Belmonte M, et al. Among authors: bennett e. Exp Hematol. 2024 Jul;135:104246. doi: 10.1016/j.exphem.2024.104246. Epub 2024 May 17. Exp Hematol. 2024. PMID: 38763471 Free article.
The Proteostasis Network is a Therapeutic Target in Acute Myeloid Leukemia.
Lam K, Kim YJ, Ong CM, Liu AZ, Zhou FJ, Sunshine MJ, Chua BA, Vicenzi S, Ford PW, Zhou JH, Hong Y, Bennett EJ, Crews LA, Ball ED, Signer RAJ. Lam K, et al. Among authors: bennett ej. bioRxiv [Preprint]. 2024 Sep 26:2024.09.24.614781. doi: 10.1101/2024.09.24.614781. bioRxiv. 2024. PMID: 39386464 Free PMC article. Preprint.
155 results