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Cervical carcinomas overexpress human trophoblast cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized monoclonal anti-Trop-2 antibody.
Varughese J, Cocco E, Bellone S, Ratner E, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Buza N, Pecorelli S, Santin AD. Varughese J, et al. Am J Obstet Gynecol. 2011 Dec;205(6):567.e1-7. doi: 10.1016/j.ajog.2011.06.093. Epub 2011 Jul 13. Am J Obstet Gynecol. 2011. PMID: 21889762 Free PMC article.
Her2/neu extracellular domain shedding in uterine serous carcinoma: implications for immunotherapy with trastuzumab.
Todeschini P, Cocco E, Bellone S, Varughese J, Lin K, Carrara L, Guzzo F, Buza N, Hui P, Silasi DA, Ratner E, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S, Santin AD. Todeschini P, et al. Among authors: varughese j. Br J Cancer. 2011 Oct 11;105(8):1176-82. doi: 10.1038/bjc.2011.369. Epub 2011 Sep 13. Br J Cancer. 2011. PMID: 21915118 Free PMC article.
Uterine serous papillary carcinomas overexpress human trophoblast-cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized anti-Trop-2 monoclonal antibody.
Varughese J, Cocco E, Bellone S, de Leon M, Bellone M, Todeschini P, Schwartz PE, Rutherford TJ, Pecorelli S, Santin AD. Varughese J, et al. Cancer. 2011 Jul 15;117(14):3163-72. doi: 10.1002/cncr.25891. Epub 2011 Jan 18. Cancer. 2011. PMID: 21246534 Free PMC article.
High-grade, chemotherapy-resistant primary ovarian carcinoma cell lines overexpress human trophoblast cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized monoclonal anti-Trop-2 antibody.
Varughese J, Cocco E, Bellone S, Bellone M, Todeschini P, Carrara L, Schwartz PE, Rutherford TJ, Pecorelli S, Santin AD. Varughese J, et al. Gynecol Oncol. 2011 Jul;122(1):171-7. doi: 10.1016/j.ygyno.2011.03.002. Epub 2011 Mar 30. Gynecol Oncol. 2011. PMID: 21453957 Free PMC article.
Expression of αV-integrins in uterine serous papillary carcinomas; implications for targeted therapy with intetumumab (CNTO 95), a fully human antagonist anti-αV-integrin antibody.
Bellone M, Cocco E, Varughese J, Bellone S, Todeschini P, El-Sahwi K, Carrara L, Guzzo F, Schwartz PE, Rutherford TJ, Pecorelli S, Marshall DJ, Santin AD. Bellone M, et al. Among authors: varughese j. Int J Gynecol Cancer. 2011 Aug;21(6):1084-90. doi: 10.1097/IGC.0b013e3182187324. Int J Gynecol Cancer. 2011. PMID: 21633302 Free PMC article.
Eradication of chemotherapy-resistant CD44+ human ovarian cancer stem cells in mice by intraperitoneal administration of Clostridium perfringens enterotoxin.
Casagrande F, Cocco E, Bellone S, Richter CE, Bellone M, Todeschini P, Siegel E, Varughese J, Arin-Silasi D, Azodi M, Rutherford TJ, Pecorelli S, Schwartz PE, Santin AD. Casagrande F, et al. Among authors: varughese j. Cancer. 2011 Dec 15;117(24):5519-28. doi: 10.1002/cncr.26215. Epub 2011 Jun 20. Cancer. 2011. PMID: 21692061 Free PMC article.
Expression of tissue factor in adenocarcinoma and squamous cell carcinoma of the uterine cervix: implications for immunotherapy with hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor.
Cocco E, Varughese J, Buza N, Bellone S, Glasgow M, Bellone M, Todeschini P, Carrara L, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S, Lockwood CJ, Santin AD. Cocco E, et al. Among authors: varughese j. BMC Cancer. 2011 Jun 22;11:263. doi: 10.1186/1471-2407-11-263. BMC Cancer. 2011. PMID: 21693061 Free PMC article.
Tissue factor expression in ovarian cancer: implications for immunotherapy with hI-con1, a factor VII-IgGF(c) chimeric protein targeting tissue factor.
Cocco E, Varughese J, Buza N, Bellone S, Lin KY, Bellone M, Todeschini P, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Carrara L, Tassi R, Pecorelli S, Lockwood CJ, Santin AD. Cocco E, et al. Among authors: varughese j. Clin Exp Metastasis. 2011 Oct;28(7):689-700. doi: 10.1007/s10585-011-9401-0. Epub 2011 Jul 2. Clin Exp Metastasis. 2011. PMID: 21725665 Free PMC article.
Trop-2 overexpression in poorly differentiated endometrial endometrioid carcinoma: implications for immunotherapy with hRS7, a humanized anti-trop-2 monoclonal antibody.
Bignotti E, Ravaggi A, Romani C, Falchetti M, Lonardi S, Facchetti F, Pecorelli S, Varughese J, Cocco E, Bellone S, Schwartz PE, Rutherford TJ, Santin AD. Bignotti E, et al. Among authors: varughese j. Int J Gynecol Cancer. 2011 Dec;21(9):1613-21. doi: 10.1097/IGC.0b013e318228f6da. Int J Gynecol Cancer. 2011. PMID: 21892093 Free PMC article.
Uterine and ovarian carcinosarcomas overexpressing Trop-2 are sensitive to hRS7, a humanized anti-Trop-2 antibody.
Raji R, Guzzo F, Carrara L, Varughese J, Cocco E, Bellone S, Betti M, Todeschini P, Gasparrini S, Ratner E, Silasi DA, Azodi M, Schwartz P, Rutherford TJ, Buza N, Pecorelli S, Santin AD. Raji R, et al. Among authors: varughese j. J Exp Clin Cancer Res. 2011 Nov 10;30(1):106. doi: 10.1186/1756-9966-30-106. J Exp Clin Cancer Res. 2011. PMID: 22075385 Free PMC article.
100 results