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ISCOMATRIX vaccines mediate CD8+ T-cell cross-priming by a MyD88-dependent signaling pathway.
Wilson NS, Yang B, Morelli AB, Koernig S, Yang A, Loeser S, Airey D, Provan L, Hass P, Braley H, Couto S, Drane D, Boyle J, Belz GT, Ashkenazi A, Maraskovsky E. Wilson NS, et al. Among authors: belz gt. Immunol Cell Biol. 2012 May;90(5):540-52. doi: 10.1038/icb.2011.71. Epub 2011 Sep 6. Immunol Cell Biol. 2012. PMID: 21894173 Free PMC article.
Helper T cells, dendritic cells and CTL Immunity.
Behrens G, Li M, Smith CM, Belz GT, Mintern J, Carbone FR, Heath WR. Behrens G, et al. Among authors: belz gt. Immunol Cell Biol. 2004 Feb;82(1):84-90. doi: 10.1111/j.1440-1711.2004.01211.x. Immunol Cell Biol. 2004. PMID: 14984599 Review.
Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity.
Wilson NS, Behrens GM, Lundie RJ, Smith CM, Waithman J, Young L, Forehan SP, Mount A, Steptoe RJ, Shortman KD, de Koning-Ward TF, Belz GT, Carbone FR, Crabb BS, Heath WR, Villadangos JA. Wilson NS, et al. Among authors: belz gt. Nat Immunol. 2006 Feb;7(2):165-72. doi: 10.1038/ni1300. Epub 2006 Jan 15. Nat Immunol. 2006. PMID: 16415871
The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture.
Schnorrer P, Behrens GM, Wilson NS, Pooley JL, Smith CM, El-Sukkari D, Davey G, Kupresanin F, Li M, Maraskovsky E, Belz GT, Carbone FR, Shortman K, Heath WR, Villadangos JA. Schnorrer P, et al. Among authors: belz gt. Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10729-34. doi: 10.1073/pnas.0601956103. Epub 2006 Jun 28. Proc Natl Acad Sci U S A. 2006. PMID: 16807294 Free PMC article.
266 results