Harper JI - Search Results

1

Human involucrin promoter mediates repression-resistant and compartment-specific LEKTI expression.

Di WL, Semenova E, Larcher F, Del Rio M, Harper JI, Thrasher AJ, Qasim W. Di WL, et al. Among authors: harper ji. Hum Gene Ther. 2012 Jan;23(1):83-90. doi: 10.1089/hum.2011.091. Hum Gene Ther. 2012. PMID: 21895535 Free PMC article.

2

Phase I study protocol for ex-vivo lentiviral gene therapy for the inherited skin disease, Netherton Syndrome.

Di WL, Mellerio JE, Bernadis C, Harper J, Abdul-Wahab A, Ghani S, Martinez-Queipo M, Hara H, McNicol AM, McGrath J, Thrasher AJ, Qasim W. Di WL, et al. Hum Gene Ther Clin Dev. 2013 Oct 18. doi: 10.1089/hum.2013.195. Online ahead of print. Hum Gene Ther Clin Dev. 2013. PMID: 24138501

3

Phase I study protocol for ex vivo lentiviral gene therapy for the inherited skin disease, Netherton syndrome.

Di WL, Mellerio JE, Bernadis C, Harper J, Abdul-Wahab A, Ghani S, Chan L, Martinez-Queipo M, Hara H, McNicol AM, Farzaneh F, McGrath J, Thrasher A, Qasim W. Di WL, et al. Hum Gene Ther Clin Dev. 2013 Dec;24(4):182-90. doi: 10.1089/humc.2013.195. Hum Gene Ther Clin Dev. 2013. PMID: 24329107 Clinical Trial.

4

Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial.

Di WL, Lwin SM, Petrova A, Bernadis C, Syed F, Farzaneh F, Moulding D, Martinez AE, Sebire NJ, Rampling D, Virasami A, Zamiri M, Wang W, Hara H, Kadiyirire T, Abdul-Wahab A, Martinez-Queipo M, Harper JI, McGrath JA, Thrasher AJ, Mellerio JE, Qasim W. Di WL, et al. Among authors: harper ji. Hum Gene Ther. 2019 Sep;30(9):1067-1078. doi: 10.1089/hum.2019.049. Epub 2019 Aug 5. Hum Gene Ther. 2019. PMID: 31288584 Clinical Trial.

5

Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin grafts.

Di WL, Larcher F, Semenova E, Talbot GE, Harper JI, Del Rio M, Thrasher AJ, Qasim W. Di WL, et al. Among authors: harper ji. Mol Ther. 2011 Feb;19(2):408-16. doi: 10.1038/mt.2010.201. Epub 2010 Sep 28. Mol Ther. 2011. PMID: 20877344 Free PMC article.

6

New role for LEKTI in skin barrier formation: label-free quantitative proteomic identification of caspase 14 as a novel target for the protease inhibitor LEKTI.

Bennett K, Callard R, Heywood W, Harper J, Jayakumar A, Clayman GL, Di WL, Mills K. Bennett K, et al. J Proteome Res. 2010 Aug 6;9(8):4289-94. doi: 10.1021/pr1003467. J Proteome Res. 2010. PMID: 20533828

7

The identification of a new role for LEKTI in the skin: The use of protein 'bait' arrays to detect defective trafficking of dermcidin in the skin of patients with Netherton syndrome.

Bennett K, Heywood W, Di WL, Harper J, Clayman GL, Jayakumar A, Callard R, Mills K. Bennett K, et al. J Proteomics. 2012 Jul 16;75(13):3925-37. doi: 10.1016/j.jprot.2012.04.045. Epub 2012 May 12. J Proteomics. 2012. PMID: 22588119

8

Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity.

Zhu Y, Underwood J, Macmillan D, Shariff L, O'Shaughnessy R, Harper JI, Pickard C, Friedmann PS, Healy E, Di WL. Zhu Y, et al. Among authors: harper ji. J Allergy Clin Immunol. 2017 Nov;140(5):1310-1322.e5. doi: 10.1016/j.jaci.2017.01.025. Epub 2017 Feb 24. J Allergy Clin Immunol. 2017. PMID: 28238749 Free article.

9

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis.

Naeem AS, Tommasi C, Cole C, Brown SJ, Zhu Y, Way B, Willis Owen SA, Moffatt M, Cookson WO, Harper JI, Di WL, Brown SJ, Reinheckel T, O'Shaughnessy RF. Naeem AS, et al. Among authors: harper ji. J Allergy Clin Immunol. 2017 Apr;139(4):1228-1241. doi: 10.1016/j.jaci.2016.09.052. Epub 2016 Nov 29. J Allergy Clin Immunol. 2017. PMID: 27913303 Free PMC article.

10

A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins.

Di WL, Hennekam RC, Callard RE, Harper JI. Di WL, et al. Among authors: harper ji. Br J Dermatol. 2009 Aug;161(2):404-12. doi: 10.1111/j.1365-2133.2009.09231.x. Epub 2009 May 12. Br J Dermatol. 2009. PMID: 19438860

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

178 results

Search Page

Filters