Sankaranarayanan A - Search Results

1

Early changes in cerebellar physiology accompany motor dysfunction in the polyglutamine disease spinocerebellar ataxia type 3.

Shakkottai VG, do Carmo Costa M, Dell'Orco JM, Sankaranarayanan A, Wulff H, Paulson HL. Shakkottai VG, et al. Among authors: sankaranarayanan a. J Neurosci. 2011 Sep 7;31(36):13002-14. doi: 10.1523/JNEUROSCI.2789-11.2011. J Neurosci. 2011. PMID: 21900579 Free PMC article.

2

Modulators of small- and intermediate-conductance calcium-activated potassium channels and their therapeutic indications.

Wulff H, Kolski-Andreaco A, Sankaranarayanan A, Sabatier JM, Shakkottai V. Wulff H, et al. Among authors: sankaranarayanan a. Curr Med Chem. 2007;14(13):1437-57. doi: 10.2174/092986707780831186. Curr Med Chem. 2007. PMID: 17584055 Review.

3

Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure.

Sankaranarayanan A, Raman G, Busch C, Schultz T, Zimin PI, Hoyer J, Köhler R, Wulff H. Sankaranarayanan A, et al. Mol Pharmacol. 2009 Feb;75(2):281-95. doi: 10.1124/mol.108.051425. Epub 2008 Oct 27. Mol Pharmacol. 2009. PMID: 18955585 Free PMC article.

4

Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases.

Schmitz A, Sankaranarayanan A, Azam P, Schmidt-Lassen K, Homerick D, Hänsel W, Wulff H. Schmitz A, et al. Among authors: sankaranarayanan a. Mol Pharmacol. 2005 Nov;68(5):1254-70. doi: 10.1124/mol.105.015669. Epub 2005 Aug 11. Mol Pharmacol. 2005. PMID: 16099841

5

Targeting effector memory T cells with the small molecule Kv1.3 blocker PAP-1 suppresses allergic contact dermatitis.

Azam P, Sankaranarayanan A, Homerick D, Griffey S, Wulff H. Azam P, et al. Among authors: sankaranarayanan a. J Invest Dermatol. 2007 Jun;127(6):1419-29. doi: 10.1038/sj.jid.5700717. Epub 2007 Feb 1. J Invest Dermatol. 2007. PMID: 17273162 Free PMC article.

6

Pharmacokinetics, toxicity, and functional studies of the selective Kv1.3 channel blocker 5-(4-phenoxybutoxy)psoralen in rhesus macaques.

Pereira LE, Villinger F, Wulff H, Sankaranarayanan A, Raman G, Ansari AA. Pereira LE, et al. Among authors: sankaranarayanan a. Exp Biol Med (Maywood). 2007 Nov;232(10):1338-54. doi: 10.3181/0705-RM-148. Exp Biol Med (Maywood). 2007. PMID: 17959847 Free PMC article.

7

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.

Beeton C, Wulff H, Standifer NE, Azam P, Mullen KM, Pennington MW, Kolski-Andreaco A, Wei E, Grino A, Counts DR, Wang PH, LeeHealey CJ, S Andrews B, Sankaranarayanan A, Homerick D, Roeck WW, Tehranzadeh J, Stanhope KL, Zimin P, Havel PJ, Griffey S, Knaus HG, Nepom GT, Gutman GA, Calabresi PA, Chandy KG. Beeton C, et al. Among authors: sankaranarayanan a. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17414-9. doi: 10.1073/pnas.0605136103. Epub 2006 Nov 6. Proc Natl Acad Sci U S A. 2006. PMID: 17088564 Free PMC article.

8

BRL 38227--a potassium channel opener, antagonizes digoxin-induced convulsions.

Chugh Y, Saha N, Sankaranarayanan A, Sharma PL. Chugh Y, et al. Among authors: sankaranarayanan a. Pharmacol Toxicol. 1993 Jul;73(1):1-2. doi: 10.1111/j.1600-0773.1993.tb01947.x. Pharmacol Toxicol. 1993. PMID: 8234183

9

Memory enhancing effects of granisetron (BRL 43694) in a passive avoidance task.

Chugh Y, Saha N, Sankaranarayanan A, Sharma PL. Chugh Y, et al. Among authors: sankaranarayanan a. Eur J Pharmacol. 1991 Oct 2;203(1):121-3. doi: 10.1016/0014-2999(91)90799-v. Eur J Pharmacol. 1991. PMID: 1665786

10

Enhancement of memory retrieval and attenuation of scopolamine-induced amnesia following administration of 5-HT3 antagonist ICS 205-930.

Chugh Y, Saha N, Sankaranarayanan A, Datta H. Chugh Y, et al. Among authors: sankaranarayanan a. Pharmacol Toxicol. 1991 Aug;69(2):105-6. doi: 10.1111/j.1600-0773.1991.tb01280.x. Pharmacol Toxicol. 1991. PMID: 1775428

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