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Long-term efficacy, safety, and tolerability of rilpivirine (RPV, TMC278) in HIV type 1-infected antiretroviral-naive patients: week 192 results from a phase IIb randomized trial.
Wilkin A, Pozniak AL, Morales-Ramirez J, Lupo SH, Santoscoy M, Grinsztejn B, Ruxrungtham K, Rimsky LT, Vanveggel S, Boven K; TMC278-C204 Study Group. Wilkin A, et al. Among authors: santoscoy m. AIDS Res Hum Retroviruses. 2012 May;28(5):437-46. doi: 10.1089/AID.2011.0050. Epub 2011 Oct 17. AIDS Res Hum Retroviruses. 2012. PMID: 21902621 Clinical Trial.
Efficacy, safety, bone and metabolic effects of HIV nucleoside reverse transcriptase inhibitor BMS-986001 (AI467003): a phase 2b randomised, controlled, partly blinded trial.
Gupta SK, McComsey GA, Lombaard J, Echevarría J, Orrell C, Avihingsanon A, Osiyemi O, Santoscoy M, Ray N, Stock DA, Joshi SR, Hanna GJ, Lataillade M. Gupta SK, et al. Among authors: santoscoy m. Lancet HIV. 2016 Jan;3(1):e13-22. doi: 10.1016/S2352-3018(15)00231-3. Epub 2015 Dec 12. Lancet HIV. 2016. PMID: 26762988 Clinical Trial.
Metabolic engineering improves transduction efficiency and downstream vector isolation by altering the lipid composition of extracellular vesicle-enclosed AAV.
Espinoza P, Cheng M, Ng C, De La Cruz D, Wasson ED, McCarthy DM, Bhide PG, Maguire CA, Santoscoy MC. Espinoza P, et al. Among authors: santoscoy mc. bioRxiv [Preprint]. 2024 Aug 19:2024.08.16.608303. doi: 10.1101/2024.08.16.608303. bioRxiv. 2024. Update in: Metab Eng. 2024 Dec 7;88:40-49. doi: 10.1016/j.ymben.2024.12.003 PMID: 39229172 Free PMC article. Updated. Preprint.
In vivo selection in non-human primates identifies AAV capsids for on-target CSF delivery to spinal cord.
Hanlon KS, Cheng M, Ferrer RM, Ryu JR, Lee B, De La Cruz D, Patel N, Espinoza P, Santoscoy MC, Gong Y, Ng C, Nguyen DM, Nammour J, Clark SW, Heine VM, Sun W, Kozarsky K, Maguire CA. Hanlon KS, et al. Among authors: santoscoy mc. Mol Ther. 2024 Aug 7;32(8):2584-2603. doi: 10.1016/j.ymthe.2024.05.040. Epub 2024 Jun 5. Mol Ther. 2024. PMID: 38845196 Free PMC article.
In vivo selection in non-human primates identifies superior AAV capsids for on-target CSF delivery to spinal cord.
Hanlon KS, Cheng M, De La Cruz D, Patel N, Santoscoy MC, Gong Y, Ng C, Nguyen DM, Nammour J, Clark SW, Kozarsky K, Maguire CA. Hanlon KS, et al. Among authors: santoscoy mc. bioRxiv [Preprint]. 2023 Sep 13:2023.09.13.557506. doi: 10.1101/2023.09.13.557506. bioRxiv. 2023. Update in: Mol Ther. 2024 Aug 7;32(8):2584-2603. doi: 10.1016/j.ymthe.2024.05.040 PMID: 37745398 Free PMC article. Updated. Preprint.
15 results