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Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL.
Mali RS, Ramdas B, Ma P, Shi J, Munugalavadla V, Sims E, Wei L, Vemula S, Nabinger SC, Goodwin CB, Chan RJ, Traina F, Visconte V, Tiu RV, Lewis TA, Stern AM, Wen Q, Crispino JD, Boswell HS, Kapur R. Mali RS, et al. Among authors: boswell hs. Cancer Cell. 2011 Sep 13;20(3):357-69. doi: 10.1016/j.ccr.2011.07.016. Cancer Cell. 2011. PMID: 21907926 Free PMC article.
Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis.
Chatterjee A, Ghosh J, Ramdas B, Mali RS, Martin H, Kobayashi M, Vemula S, Canela VH, Waskow ER, Visconte V, Tiu RV, Smith CC, Shah N, Bunting KD, Boswell HS, Liu Y, Chan RJ, Kapur R. Chatterjee A, et al. Among authors: boswell hs. Cell Rep. 2014 Nov 20;9(4):1333-48. doi: 10.1016/j.celrep.2014.10.039. Epub 2014 Nov 13. Cell Rep. 2014. PMID: 25456130 Free PMC article.
Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development.
Nabinger SC, Chen S, Gao R, Yao C, Kobayashi M, Vemula S, Fahey AC, Wang C, Daniels C, Boswell HS, Sandusky GE, Mayo LD, Kapur R, Liu Y. Nabinger SC, et al. Among authors: boswell hs. Leukemia. 2019 Jun;33(6):1535-1539. doi: 10.1038/s41375-019-0377-0. Epub 2019 Jan 23. Leukemia. 2019. PMID: 30675010 Free PMC article. No abstract available.
The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo.
Nabinger SC, Li XJ, Ramdas B, He Y, Zhang X, Zeng L, Richine B, Bowling JD, Fukuda S, Goenka S, Liu Z, Feng GS, Yu M, Sandusky GE, Boswell HS, Zhang ZY, Kapur R, Chan RJ. Nabinger SC, et al. Among authors: boswell hs. Leukemia. 2013 Feb;27(2):398-408. doi: 10.1038/leu.2012.308. Epub 2012 Oct 22. Leukemia. 2013. PMID: 23103841 Free PMC article.
Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.
Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, Wolf ER, Ramdas B, Cai Z, Gao H, Luo N, Sun Y, Wong TN, Link DC, Liu Y, Boswell HS, Mayo LD, Huang G, Kapur R, Yoder MC, Broxmeyer HE, Gao Z, Liu Y. Chen S, et al. Among authors: boswell hs. Nat Commun. 2019 Dec 11;10(1):5649. doi: 10.1038/s41467-019-13542-2. Nat Commun. 2019. PMID: 31827082 Free PMC article.
Author Correction: Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.
Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, Wolf ER, Ramdas B, Cai Z, Gao H, Luo N, Sun Y, Wong TN, Link DC, Liu Y, Boswell HS, Mayo LD, Huang G, Kapur R, Yoder MC, Broxmeyer HE, Gao Z, Liu Y. Chen S, et al. Among authors: boswell hs. Nat Commun. 2020 Jul 28;11(1):3856. doi: 10.1038/s41467-020-17555-0. Nat Commun. 2020. PMID: 32724180 Free PMC article.
Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner.
Wang L, Zhang H, Rodriguez S, Cao L, Parish J, Mumaw C, Zollman A, Kamoka MM, Mu J, Chen DZ, Srour EF, Chitteti BR, HogenEsch H, Tu X, Bellido TM, Boswell HS, Manshouri T, Verstovsek S, Yoder MC, Kapur R, Cardoso AA, Carlesso N. Wang L, et al. Among authors: boswell hs. Cell Stem Cell. 2014 Jul 3;15(1):51-65. doi: 10.1016/j.stem.2014.04.021. Cell Stem Cell. 2014. PMID: 24996169 Free PMC article.
Phosphatase PRL2 promotes AML1-ETO-induced acute myeloid leukemia.
Kobayashi M, Chen S, Bai Y, Yao C, Gao R, Sun XJ, Mu C, Twiggs TA, Yu ZH, Boswell HS, Yoder MC, Kapur R, Mulloy JC, Zhang ZY, Liu Y. Kobayashi M, et al. Among authors: boswell hs. Leukemia. 2017 Jun;31(6):1453-1457. doi: 10.1038/leu.2017.67. Epub 2017 Feb 21. Leukemia. 2017. PMID: 28220038 Free PMC article. No abstract available.
74 results