Characterization of mice with targeted deletion of the gene encoding core 2 beta1,6-N-acetylglucosaminyltransferase-2.
Stone EL, Lee SH, Ismail MN, Fukuda M.
Stone EL, et al.
Methods Enzymol. 2010;479:155-72. doi: 10.1016/S0076-6879(10)79009-1.
Methods Enzymol. 2010.
PMID: 20816165
Unexpectedly, we saw that the loss of C2GnT2 and especially the loss of all three C2GnTs resulted in the expression of elongated O-mannose structures in the stomach, suggesting that the elongation of these structures is controlled by competition for UDP-GlcNAc [Stone, E …
Unexpectedly, we saw that the loss of C2GnT2 and especially the loss of all three C2GnTs resulted in the expression of elongated O-mannose s …