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Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines.
Somwar R, Erdjument-Bromage H, Larsson E, Shum D, Lockwood WW, Yang G, Sander C, Ouerfelli O, Tempst PJ, Djaballah H, Varmus HE. Somwar R, et al. Among authors: ouerfelli o. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16375-80. doi: 10.1073/pnas.1113554108. Epub 2011 Sep 19. Proc Natl Acad Sci U S A. 2011. PMID: 21930909 Free PMC article.
Sequence characteristics of functional siRNAs.
Jagla B, Aulner N, Kelly PD, Song D, Volchuk A, Zatorski A, Shum D, Mayer T, De Angelis DA, Ouerfelli O, Rutishauser U, Rothman JE. Jagla B, et al. Among authors: ouerfelli o. RNA. 2005 Jun;11(6):864-72. doi: 10.1261/rna.7275905. RNA. 2005. PMID: 15923373 Free PMC article.
Diverted total synthesis leads to the generation of promising cell-migration inhibitors for treatment of tumor metastasis: in vivo and mechanistic studies on the migrastatin core ether analog.
Oskarsson T, Nagorny P, Krauss IJ, Perez L, Mandal M, Yang G, Ouerfelli O, Xiao D, Moore MA, Massagué J, Danishefsky SJ. Oskarsson T, et al. Among authors: ouerfelli o. J Am Chem Soc. 2010 Mar 10;132(9):3224-8. doi: 10.1021/ja9101503. J Am Chem Soc. 2010. PMID: 20155906 Free PMC article.
Inhibition of human peptide deformylase disrupts mitochondrial function.
Escobar-Alvarez S, Gardner J, Sheth A, Manfredi G, Yang G, Ouerfelli O, Heaney ML, Scheinberg DA. Escobar-Alvarez S, et al. Among authors: ouerfelli o. Mol Cell Biol. 2010 Nov;30(21):5099-109. doi: 10.1128/MCB.00469-10. Epub 2010 Aug 30. Mol Cell Biol. 2010. PMID: 20805355 Free PMC article.
74 results