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Page 1
A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.
O'Leary JC 3rd, Dharia S, Blair LJ, Brady S, Johnson AG, Peters M, Cheung-Flynn J, Cox MB, de Erausquin G, Weeber EJ, Jinwal UK, Dickey CA. O'Leary JC 3rd, et al. Among authors: dickey ca. PLoS One. 2011;6(9):e24840. doi: 10.1371/journal.pone.0024840. Epub 2011 Sep 15. PLoS One. 2011. PMID: 21935478 Free PMC article.
Akt and CHIP coregulate tau degradation through coordinated interactions.
Dickey CA, Koren J, Zhang YJ, Xu YF, Jinwal UK, Birnbaum MJ, Monks B, Sun M, Cheng JQ, Patterson C, Bailey RM, Dunmore J, Soresh S, Leon C, Morgan D, Petrucelli L. Dickey CA, et al. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3622-7. doi: 10.1073/pnas.0709180105. Epub 2008 Feb 21. Proc Natl Acad Sci U S A. 2008. PMID: 18292230 Free PMC article.
Chaperone signalling complexes in Alzheimer's disease.
Koren J 3rd, Jinwal UK, Lee DC, Jones JR, Shults CL, Johnson AG, Anderson LJ, Dickey CA. Koren J 3rd, et al. Among authors: dickey ca. J Cell Mol Med. 2009 Apr;13(4):619-30. doi: 10.1111/j.1582-4934.2008.00557.x. J Cell Mol Med. 2009. PMID: 19449461 Free PMC article. Review.
Chemical manipulation of hsp70 ATPase activity regulates tau stability.
Jinwal UK, Miyata Y, Koren J 3rd, Jones JR, Trotter JH, Chang L, O'Leary J, Morgan D, Lee DC, Shults CL, Rousaki A, Weeber EJ, Zuiderweg ER, Gestwicki JE, Dickey CA. Jinwal UK, et al. Among authors: dickey ca. J Neurosci. 2009 Sep 30;29(39):12079-88. doi: 10.1523/JNEUROSCI.3345-09.2009. J Neurosci. 2009. PMID: 19793966 Free PMC article.
Facilitating Akt clearance via manipulation of Hsp70 activity and levels.
Koren J 3rd, Jinwal UK, Jin Y, O'Leary J, Jones JR, Johnson AG, Blair LJ, Abisambra JF, Chang L, Miyata Y, Cheng AM, Guo J, Cheng JQ, Gestwicki JE, Dickey CA. Koren J 3rd, et al. Among authors: dickey ca. J Biol Chem. 2010 Jan 22;285(4):2498-505. doi: 10.1074/jbc.M109.057208. Epub 2009 Nov 4. J Biol Chem. 2010. PMID: 19889640 Free PMC article.
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.
Jinwal UK, Koren J 3rd, Borysov SI, Schmid AB, Abisambra JF, Blair LJ, Johnson AG, Jones JR, Shults CL, O'Leary JC 3rd, Jin Y, Buchner J, Cox MB, Dickey CA. Jinwal UK, et al. Among authors: dickey ca. J Neurosci. 2010 Jan 13;30(2):591-9. doi: 10.1523/JNEUROSCI.4815-09.2010. J Neurosci. 2010. PMID: 20071522 Free PMC article.
Hsc70 rapidly engages tau after microtubule destabilization.
Jinwal UK, O'Leary JC 3rd, Borysov SI, Jones JR, Li Q, Koren J 3rd, Abisambra JF, Vestal GD, Lawson LY, Johnson AG, Blair LJ, Jin Y, Miyata Y, Gestwicki JE, Dickey CA. Jinwal UK, et al. Among authors: dickey ca. J Biol Chem. 2010 May 28;285(22):16798-805. doi: 10.1074/jbc.M110.113753. Epub 2010 Mar 22. J Biol Chem. 2010. PMID: 20308058 Free PMC article.
137 results