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Page 1
Steroidal C-21 mercapto derivatives as dissociated steroids: discovery of an inhaled dissociated steroid.
Biju P, McCormick K, Aslanian R, Berlin M, Solomon D, Chapman R, McLeod R, Prelusky D, Eckel S, Kelly G, Natiello M, House A, Fernandez X, Bitar R, Phillips J, Anthes J. Biju P, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6343-7. doi: 10.1016/j.bmcl.2011.08.108. Epub 2011 Aug 31. Bioorg Med Chem Lett. 2011. PMID: 21944381
Discovery of oral and inhaled PDE4 inhibitors.
Ting PC, Lee JF, Kuang R, Cao J, Gu D, Huang Y, Liu Z, Aslanian RG, Feng KI, Prelusky D, Lamca J, House A, Phillips JE, Wang P, Wu P, Lundell D, Chapman RW, Celly CS. Ting PC, et al. Among authors: aslanian rg. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5528-32. doi: 10.1016/j.bmcl.2013.08.056. Epub 2013 Aug 21. Bioorg Med Chem Lett. 2013. PMID: 24018187
Steroidal C-21 heteroaryl thioethers (Part 2): discovery of orally bioavailable selective glucocorticoid receptor modulators (dissociated steroids).
Biju P, McCormick K, Aslanian R, Berlin M, Solomon D, Wang H, Lee YJ, Bitar R, Prelusky D, McLeod R, Jia Y, Fernandez X, Eckel S, House A, Lieber G, Jimenez J, Kelly G, Chapman R, Phillips J, Anthes J. Biju P, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1086-90. doi: 10.1016/j.bmcl.2011.11.120. Epub 2011 Dec 7. Bioorg Med Chem Lett. 2012. PMID: 22197391
Steroidal C-21 heteroaryl thioethers. Part 3: pregn-4-eno-[3,2-c]pyrazole fused A ring modified steroids as selective glucocorticoid receptor modulators (dissociated steroids).
Biju P, Wang H, Anthes J, McCormick K, Aslanian R, Berlin M, Bitar R, Lim YH, Lee YJ, Prelusky D, Mcleod R, Jia Y, Fernandez X, Lieber G, Jimenez J, Eckel S, House A, Chapman R, Phillips J. Biju P, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2012 May 1;22(9):3291-5. doi: 10.1016/j.bmcl.2012.03.015. Epub 2012 Mar 11. Bioorg Med Chem Lett. 2012. PMID: 22465636
Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold.
Vaccaro WD, Sher R, Berlin M, Shih NY, Aslanian R, Schwerdt JH, McCormick KD, Piwinski JJ, West RE Jr, Anthes JC, Williams SM, Wu RL, She HS, Rivelli MA, Mutter JC, Corboz MR, Hey JA, Favreau L. Vaccaro WD, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2006 Jan 15;16(2):395-9. doi: 10.1016/j.bmcl.2005.09.076. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246552
115 results