Coscoy L - Search Results

1

Expression of the RAE-1 family of stimulatory NK-cell ligands requires activation of the PI3K pathway during viral infection and transformation.

Tokuyama M, Lorin C, Delebecque F, Jung H, Raulet DH, Coscoy L. Tokuyama M, et al. Among authors: coscoy l. PLoS Pathog. 2011 Sep;7(9):e1002265. doi: 10.1371/journal.ppat.1002265. Epub 2011 Sep 22. PLoS Pathog. 2011. PMID: 21966273 Free PMC article.

2

DNA mismanagement leads to immune system oversight.

Coscoy L, Raulet DH. Coscoy L, et al. Cell. 2007 Nov 30;131(5):836-8. doi: 10.1016/j.cell.2007.11.012. Cell. 2007. PMID: 18045527 Free PMC article.

3

Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress.

Nice TJ, Coscoy L, Raulet DH. Nice TJ, et al. Among authors: coscoy l. J Exp Med. 2009 Feb 16;206(2):287-98. doi: 10.1084/jem.20081335. Epub 2009 Jan 26. J Exp Med. 2009. PMID: 19171762 Free PMC article.

4

Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.

Nice TJ, Deng W, Coscoy L, Raulet DH. Nice TJ, et al. Among authors: coscoy l. J Immunol. 2010 Nov 1;185(9):5369-76. doi: 10.4049/jimmunol.1000247. Epub 2010 Sep 24. J Immunol. 2010. PMID: 20870941 Free PMC article.

5

A role for host activation-induced cytidine deaminase in innate immune defense against KSHV.

Bekerman E, Jeon D, Ardolino M, Coscoy L. Bekerman E, et al. Among authors: coscoy l. PLoS Pathog. 2013;9(11):e1003748. doi: 10.1371/journal.ppat.1003748. Epub 2013 Nov 7. PLoS Pathog. 2013. PMID: 24244169 Free PMC article. Clinical Trial.

6

A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells.

Gowen BG, Chim B, Marceau CD, Greene TT, Burr P, Gonzalez JR, Hesser CR, Dietzen PA, Russell T, Iannello A, Coscoy L, Sentman CL, Carette JE, Muljo SA, Raulet DH. Gowen BG, et al. Among authors: coscoy l. Elife. 2015 Nov 13;4:e08474. doi: 10.7554/eLife.08474. Elife. 2015. PMID: 26565589 Free PMC article.

7

A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression.

Greene TT, Tokuyama M, Knudsen GM, Kunz M, Lin J, Greninger AL, DeFilippis VR, DeRisi JL, Raulet DH, Coscoy L. Greene TT, et al. Among authors: coscoy l. Elife. 2016 Nov 22;5:e14749. doi: 10.7554/eLife.14749. Elife. 2016. PMID: 27874833 Free PMC article.

8

Dysregulated cellular functions and cell stress pathways provide critical cues for activating and targeting natural killer cells to transformed and infected cells.

Raulet DH, Marcus A, Coscoy L. Raulet DH, et al. Among authors: coscoy l. Immunol Rev. 2017 Nov;280(1):93-101. doi: 10.1111/imr.12600. Immunol Rev. 2017. PMID: 29027233 Free PMC article. Review.

9

Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon production.

Young JA, Sermwittayawong D, Kim HJ, Nandu S, An N, Erdjument-Bromage H, Tempst P, Coscoy L, Winoto A. Young JA, et al. Among authors: coscoy l. J Biol Chem. 2011 Feb 25;286(8):6521-31. doi: 10.1074/jbc.M110.172288. Epub 2010 Dec 23. J Biol Chem. 2011. PMID: 21183682 Free PMC article.

10

Suppression of TLR9 immunostimulatory motifs in the genome of a gammaherpesvirus.

Pezda AC, Penn A, Barton GM, Coscoy L. Pezda AC, et al. Among authors: coscoy l. J Immunol. 2011 Jul 15;187(2):887-96. doi: 10.4049/jimmunol.1003737. Epub 2011 Jun 10. J Immunol. 2011. PMID: 21666062 Free PMC article.

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