Arkell RM - Search Results

1

Overexpression of the Flii gene increases dermal-epidermal blistering in an autoimmune ColVII mouse model of epidermolysis bullosa acquisita.

Kopecki Z, Arkell RM, Strudwick XL, Hirose M, Ludwig RJ, Kern JS, Bruckner-Tuderman L, Zillikens D, Murrell DF, Cowin AJ. Kopecki Z, et al. Among authors: arkell rm. J Pathol. 2011 Nov;225(3):401-13. doi: 10.1002/path.2973. Epub 2011 Sep 26. J Pathol. 2011. PMID: 21984127

2

Attenuation of Flightless I, an actin-remodelling protein, improves burn injury repair via modulation of transforming growth factor (TGF)-beta1 and TGF-beta3.

Adams DH, Ruzehaji N, Strudwick XL, Greenwood JE, Campbell HD, Arkell R, Cowin AJ. Adams DH, et al. Br J Dermatol. 2009 Aug;161(2):326-36. doi: 10.1111/j.1365-2133.2009.09296.x. Epub 2009 Jun 9. Br J Dermatol. 2009. PMID: 19519830

3

Flightless I regulates hemidesmosome formation and integrin-mediated cellular adhesion and migration during wound repair.

Kopecki Z, Arkell R, Powell BC, Cowin AJ. Kopecki Z, et al. J Invest Dermatol. 2009 Aug;129(8):2031-45. doi: 10.1038/jid.2008.461. Epub 2009 Feb 12. J Invest Dermatol. 2009. PMID: 19212345 Free article.

4

Flightless I over-expression impairs skin barrier development, function and recovery following skin blistering.

Kopecki Z, Yang GN, Arkell RM, Jackson JE, Melville E, Iwata H, Ludwig RJ, Zillikens D, Murrell DF, Cowin AJ. Kopecki Z, et al. Among authors: arkell rm. J Pathol. 2014 Apr;232(5):541-52. doi: 10.1002/path.4323. Epub 2014 Feb 5. J Pathol. 2014. PMID: 24375017

5

Regeneration of hair follicles is modulated by flightless I (Flii) in a rodent vibrissa model.

Waters JM, Lindo JE, Arkell RM, Cowin AJ. Waters JM, et al. Among authors: arkell rm. J Invest Dermatol. 2011 Apr;131(4):838-47. doi: 10.1038/jid.2010.393. Epub 2010 Dec 30. J Invest Dermatol. 2011. PMID: 21191408 Free article.

6

Flightless I is a key regulator of the fibroproliferative process in hypertrophic scarring and a target for a novel antiscarring therapy.

Cameron AM, Turner CT, Adams DH, Jackson JE, Melville E, Arkell RM, Anderson PJ, Cowin AJ. Cameron AM, et al. Among authors: arkell rm. Br J Dermatol. 2016 Apr;174(4):786-94. doi: 10.1111/bjd.14263. Epub 2016 Jan 9. Br J Dermatol. 2016. PMID: 26521845

7

The influence of Flightless I on Toll-like-receptor-mediated inflammation in a murine model of diabetic wound healing.

Ruzehaji N, Mills SJ, Melville E, Arkell R, Fitridge R, Cowin AJ. Ruzehaji N, et al. Biomed Res Int. 2013;2013:389792. doi: 10.1155/2013/389792. Epub 2013 Feb 18. Biomed Res Int. 2013. PMID: 23555084 Free PMC article.

8

Mouse strains for the ubiquitous or conditional overexpression of the Flii gene.

Thomsen N, Chappell A, Ali RG, Jones T, Adams DH, Matthaei KI, Campbell HD, Cowin AJ, Arkell RM. Thomsen N, et al. Among authors: arkell rm. Genesis. 2011 Aug;49(8):681-8. doi: 10.1002/dvg.20735. Epub 2011 Jul 22. Genesis. 2011. PMID: 21786402

9

Attenuation of flightless I improves wound healing and enhances angiogenesis in a murine model of type 1 diabetes.

Ruzehaji N, Kopecki Z, Melville E, Appleby SL, Bonder CS, Arkell RM, Fitridge R, Cowin AJ. Ruzehaji N, et al. Among authors: arkell rm. Diabetologia. 2014 Feb;57(2):402-12. doi: 10.1007/s00125-013-3107-6. Epub 2013 Nov 29. Diabetologia. 2014. PMID: 24292564

10

Fibroblast-specific upregulation of Flightless I impairs wound healing.

Turner CT, Waters JM, Jackson JE, Arkell RM, Cowin AJ. Turner CT, et al. Among authors: arkell rm. Exp Dermatol. 2015 Sep;24(9):692-7. doi: 10.1111/exd.12751. Epub 2015 Jul 14. Exp Dermatol. 2015. PMID: 25959103

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