Ming X - Search Results

1

Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides.

Juliano RL, Ming X, Nakagawa O. Juliano RL, et al. Among authors: ming x. Bioconjug Chem. 2012 Feb 15;23(2):147-57. doi: 10.1021/bc200377d. Epub 2011 Oct 27. Bioconjug Chem. 2012. PMID: 21992697 Free PMC article. Review.

2

Biological barriers to therapy with antisense and siRNA oligonucleotides.

Juliano R, Bauman J, Kang H, Ming X. Juliano R, et al. Among authors: ming x. Mol Pharm. 2009 May-Jun;6(3):686-95. doi: 10.1021/mp900093r. Mol Pharm. 2009. PMID: 19397332 Free PMC article. Review.

3

Receptors, endocytosis, and trafficking: the biological basis of targeted delivery of antisense and siRNA oligonucleotides.

Juliano RL, Carver K, Cao C, Ming X. Juliano RL, et al. Among authors: ming x. J Drug Target. 2013 Jan;21(1):27-43. doi: 10.3109/1061186X.2012.740674. Epub 2012 Nov 19. J Drug Target. 2013. PMID: 23163768 Free PMC article. Review.

4

High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides.

Yang B, Ming X, Cao C, Laing B, Yuan A, Porter MA, Hull-Ryde EA, Maddry J, Suto M, Janzen WP, Juliano RL. Yang B, et al. Among authors: ming x. Nucleic Acids Res. 2015 Feb 27;43(4):1987-96. doi: 10.1093/nar/gkv060. Epub 2015 Feb 6. Nucleic Acids Res. 2015. PMID: 25662226 Free PMC article.

5

A Novel Family of Small Molecules that Enhance the Intracellular Delivery and Pharmacological Effectiveness of Antisense and Splice Switching Oligonucleotides.

Wang L, Ariyarathna Y, Ming X, Yang B, James LI, Kreda SM, Porter M, Janzen W, Juliano RL. Wang L, et al. Among authors: ming x. ACS Chem Biol. 2017 Aug 18;12(8):1999-2007. doi: 10.1021/acschembio.7b00242. Epub 2017 Jul 14. ACS Chem Biol. 2017. PMID: 28703575 Free PMC article.

6

Structure-activity relationships and cellular mechanism of action of small molecules that enhance the delivery of oligonucleotides.

Juliano RL, Wang L, Tavares F, Brown EG, James L, Ariyarathna Y, Ming X, Mao C, Suto M. Juliano RL, et al. Among authors: ming x. Nucleic Acids Res. 2018 Feb 28;46(4):1601-1613. doi: 10.1093/nar/gkx1320. Nucleic Acids Res. 2018. PMID: 29361039 Free PMC article.

7

The biological effect of an antisense oligonucleotide depends on its route of endocytosis and trafficking.

Alam MR, Ming X, Dixit V, Fisher M, Chen X, Juliano RL. Alam MR, et al. Among authors: ming x. Oligonucleotides. 2010 Apr;20(2):103-9. doi: 10.1089/oli.2009.0211. Oligonucleotides. 2010. PMID: 20038250 Free PMC article.

8

Targeted intracellular delivery of antisense oligonucleotides via conjugation with small-molecule ligands.

Nakagawa O, Ming X, Huang L, Juliano RL. Nakagawa O, et al. Among authors: ming x. J Am Chem Soc. 2010 Jul 7;132(26):8848-9. doi: 10.1021/ja102635c. J Am Chem Soc. 2010. PMID: 20550198 Free PMC article.

9

Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor.

Ming X, Alam MR, Fisher M, Yan Y, Chen X, Juliano RL. Ming X, et al. Nucleic Acids Res. 2010 Oct;38(19):6567-76. doi: 10.1093/nar/gkq534. Epub 2010 Jun 15. Nucleic Acids Res. 2010. PMID: 20551131 Free PMC article.

10

Unconventional internalization mechanisms underlying functional delivery of antisense oligonucleotides via cationic lipoplexes and polyplexes.

Ming X, Sato K, Juliano RL. Ming X, et al. J Control Release. 2011 Jul 15;153(1):83-92. doi: 10.1016/j.jconrel.2011.04.029. Epub 2011 May 4. J Control Release. 2011. PMID: 21571016 Free PMC article.

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