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Page 1
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.
Rayner KJ, Esau CC, Hussain FN, McDaniel AL, Marshall SM, van Gils JM, Ray TD, Sheedy FJ, Goedeke L, Liu X, Khatsenko OG, Kaimal V, Lees CJ, Fernandez-Hernando C, Fisher EA, Temel RE, Moore KJ. Rayner KJ, et al. Among authors: kaimal v. Nature. 2011 Oct 19;478(7369):404-7. doi: 10.1038/nature10486. Nature. 2011. PMID: 22012398 Free PMC article.
microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.
Hajarnis S, Lakhia R, Yheskel M, Williams D, Sorourian M, Liu X, Aboudehen K, Zhang S, Kersjes K, Galasso R, Li J, Kaimal V, Lockton S, Davis S, Flaten A, Johnson JA, Holland WL, Kusminski CM, Scherer PE, Harris PC, Trudel M, Wallace DP, Igarashi P, Lee EC, Androsavich JR, Patel V. Hajarnis S, et al. Among authors: kaimal v. Nat Commun. 2017 Feb 16;8:14395. doi: 10.1038/ncomms14395. Nat Commun. 2017. PMID: 28205547 Free PMC article.
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS. Gomez IG, et al. Among authors: kaimal v. J Clin Invest. 2015 Jan;125(1):141-56. doi: 10.1172/JCI75852. Epub 2014 Nov 21. J Clin Invest. 2015. PMID: 25415439 Free PMC article.
MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways.
Chau BN, Xin C, Hartner J, Ren S, Castano AP, Linn G, Li J, Tran PT, Kaimal V, Huang X, Chang AN, Li S, Kalra A, Grafals M, Portilla D, MacKenna DA, Orkin SH, Duffield JS. Chau BN, et al. Among authors: kaimal v. Sci Transl Med. 2012 Feb 15;4(121):121ra18. doi: 10.1126/scitranslmed.3003205. Sci Transl Med. 2012. PMID: 22344686 Free PMC article.
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth.
Huang X, Magnus J, Kaimal V, Karmali P, Li J, Walls M, Prudente R, Sung E, Sorourian M, Lee R, Davis S, Yang X, Estrella H, Lee EC, Chau BN, Pavlicek A, Zabludoff S. Huang X, et al. Among authors: kaimal v. Mol Cancer Ther. 2017 May;16(5):905-913. doi: 10.1158/1535-7163.MCT-16-0613. Epub 2017 Feb 6. Mol Cancer Ther. 2017. PMID: 28167506
Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit.
Bertero T, Cottrill KA, Lu Y, Haeger CM, Dieffenbach P, Annis S, Hale A, Bhat B, Kaimal V, Zhang YY, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Black SM, Fratz S, Fineman JR, Vargas SO, Haley KJ, Waxman AB, Chau BN, Fredenburgh LE, Chan SY. Bertero T, et al. Among authors: kaimal v. Cell Rep. 2015 Nov 3;13(5):1016-32. doi: 10.1016/j.celrep.2015.09.049. Epub 2015 Oct 22. Cell Rep. 2015. PMID: 26565914 Free PMC article.
miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients.
Akers JC, Ramakrishnan V, Kim R, Phillips S, Kaimal V, Mao Y, Hua W, Yang I, Fu CC, Nolan J, Nakano I, Yang Y, Beaulieu M, Carter BS, Chen CC. Akers JC, et al. Among authors: kaimal v. J Neurooncol. 2015 Jun;123(2):205-16. doi: 10.1007/s11060-015-1784-3. Epub 2015 Apr 23. J Neurooncol. 2015. PMID: 25903655 Free PMC article.
Shift of microRNA profile upon orthotopic xenografting of glioblastoma spheroid cultures.
Halle B, Thomassen M, Venkatesan R, Kaimal V, Marcusson EG, Munthe S, Sørensen MD, Aaberg-Jessen C, Jensen SS, Meyer M, Kruse TA, Christiansen H, Schmidt S, Mollenhauer J, Schulz MK, Andersen C, Kristensen BW. Halle B, et al. Among authors: kaimal v. J Neurooncol. 2016 Jul;128(3):395-404. doi: 10.1007/s11060-016-2125-x. Epub 2016 Apr 11. J Neurooncol. 2016. PMID: 27063952
Anti-miR-17 therapy delays tumorigenesis in MYC-driven hepatocellular carcinoma (HCC).
Dhanasekaran R, Gabay-Ryan M, Baylot V, Lai I, Mosley A, Huang X, Zabludoff S, Li J, Kaimal V, Karmali P, Felsher DW. Dhanasekaran R, et al. Among authors: kaimal v. Oncotarget. 2017 Nov 9;9(5):5517-5528. doi: 10.18632/oncotarget.22342. eCollection 2018 Jan 19. Oncotarget. 2017. PMID: 29464015 Free PMC article.
30 results