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Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.
Gallego X, Molas S, Amador-Arjona A, Marks MJ, Robles N, Murtra P, Armengol L, Fernández-Montes RD, Gratacòs M, Pumarola M, Cabrera R, Maldonado R, Sabrià J, Estivill X, Dierssen M. Gallego X, et al. Among authors: fernandez montes rd. Amino Acids. 2012 Aug;43(2):897-909. doi: 10.1007/s00726-011-1149-y. Epub 2011 Nov 19. Amino Acids. 2012. PMID: 22101982