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Methotrexate and low-dose prednisolone downregulate osteoclast function by decreasing receptor activator of nuclear factor-κβ expression in monocytes from patients with early rheumatoid arthritis.
Perpétuo IP, Caetano-Lopes J, Rodrigues AM, Campanilho-Marques R, Ponte C, Canhão H, Ainola M, Fonseca JE. Perpétuo IP, et al. RMD Open. 2017 Jul 13;3(1):e000365. doi: 10.1136/rmdopen-2016-000365. eCollection 2017. RMD Open. 2017. PMID: 28955481 Free PMC article.
Chronic arthritis leads to disturbances in the bone collagen network.
Caetano-Lopes J, Nery AM, Canhão H, Duarte J, Cascão R, Rodrigues A, Perpétuo IP, Abdulghani S, Amaral PM, Sakaguchi S, Konttinen YT, Graça L, Vaz MF, Fonseca JE. Caetano-Lopes J, et al. Among authors: perpetuo ip. Arthritis Res Ther. 2010;12(1):R9. doi: 10.1186/ar2908. Epub 2010 Jan 15. Arthritis Res Ther. 2010. PMID: 20078856 Free PMC article.
Upregulation of inflammatory genes and downregulation of sclerostin gene expression are key elements in the early phase of fragility fracture healing.
Caetano-Lopes J, Lopes A, Rodrigues A, Fernandes D, Perpétuo IP, Monjardino T, Lucas R, Monteiro J, Konttinen YT, Canhão H, Fonseca JE. Caetano-Lopes J, et al. Among authors: perpetuo ip. PLoS One. 2011 Feb 11;6(2):e16947. doi: 10.1371/journal.pone.0016947. PLoS One. 2011. PMID: 21347301 Free PMC article.
18 results