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Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease.
Shen Y, Muramatsu SI, Ikeguchi K, Fujimoto KI, Fan DS, Ogawa M, Mizukami H, Urabe M, Kume A, Nagatsu I, Urano F, Suzuki T, Ichinose H, Nagatsu T, Monahan J, Nakano I, Ozawa K. Shen Y, et al. Among authors: muramatsu si. Hum Gene Ther. 2000 Jul 20;11(11):1509-19. doi: 10.1089/10430340050083243. Hum Gene Ther. 2000. PMID: 10945765
Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes.
Muramatsu S, Fujimoto K, Ikeguchi K, Shizuma N, Kawasaki K, Ono F, Shen Y, Wang L, Mizukami H, Kume A, Matsumura M, Nagatsu I, Urano F, Ichinose H, Nagatsu T, Terao K, Nakano I, Ozawa K. Muramatsu S, et al. Hum Gene Ther. 2002 Feb 10;13(3):345-54. doi: 10.1089/10430340252792486. Hum Gene Ther. 2002. PMID: 11860702
Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons.
Kadkhodaei B, Ito T, Joodmardi E, Mattsson B, Rouillard C, Carta M, Muramatsu S, Sumi-Ichinose C, Nomura T, Metzger D, Chambon P, Lindqvist E, Larsson NG, Olson L, Björklund A, Ichinose H, Perlmann T. Kadkhodaei B, et al. Among authors: muramatsu s. J Neurosci. 2009 Dec 16;29(50):15923-32. doi: 10.1523/JNEUROSCI.3910-09.2009. J Neurosci. 2009. PMID: 20016108 Free PMC article.
AADC deficiency: occurring in humans, modeled in rodents.
Hwu WL, Lee NC, Chien YH, Muramatsu S, Ichinose H. Hwu WL, et al. Among authors: muramatsu s. Adv Pharmacol. 2013;68:273-84. doi: 10.1016/B978-0-12-411512-5.00013-0. Adv Pharmacol. 2013. PMID: 24054149 Review.
Isolation and characterization of patient-derived, toxic, high mass amyloid beta-protein (Abeta) assembly from Alzheimer disease brains.
Noguchi A, Matsumura S, Dezawa M, Tada M, Yanazawa M, Ito A, Akioka M, Kikuchi S, Sato M, Ideno S, Noda M, Fukunari A, Muramatsu S, Itokazu Y, Sato K, Takahashi H, Teplow DB, Nabeshima Y, Kakita A, Imahori K, Hoshi M. Noguchi A, et al. Among authors: muramatsu s. J Biol Chem. 2009 Nov 20;284(47):32895-905. doi: 10.1074/jbc.M109.000208. Epub 2009 Sep 15. J Biol Chem. 2009. PMID: 19759000 Free PMC article.
623 results