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B cells are critical to T-cell-mediated antitumor immunity induced by a combined immune-stimulatory/conditionally cytotoxic therapy for glioblastoma.
Candolfi M, Curtin JF, Yagiz K, Assi H, Wibowo MK, Alzadeh GE, Foulad D, Muhammad AK, Salehi S, Keech N, Puntel M, Liu C, Sanderson NR, Kroeger KM, Dunn R, Martins G, Lowenstein PR, Castro MG. Candolfi M, et al. Among authors: curtin jf. Neoplasia. 2011 Oct;13(10):947-60. doi: 10.1593/neo.11024. Neoplasia. 2011. PMID: 22028620 Free PMC article.
Study of the efficacy, biodistribution, and safety profile of therapeutic gutless adenovirus vectors as a prelude to a phase I clinical trial for glioblastoma.
Muhammad AK, Puntel M, Candolfi M, Salem A, Yagiz K, Farrokhi C, Kroeger KM, Xiong W, Curtin JF, Liu C, Lawrence K, Bondale NS, Lerner J, Baker GJ, Foulad D, Pechnick RN, Palmer D, Ng P, Lowenstein PR, Castro MG. Muhammad AK, et al. Among authors: curtin jf. Clin Pharmacol Ther. 2010 Aug;88(2):204-13. doi: 10.1038/clpt.2009.260. Epub 2010 Feb 17. Clin Pharmacol Ther. 2010. PMID: 20164833 Free PMC article.
HMGB1 mediates endogenous TLR2 activation and brain tumor regression.
Curtin JF, Liu N, Candolfi M, Xiong W, Assi H, Yagiz K, Edwards MR, Michelsen KS, Kroeger KM, Liu C, Muhammad AK, Clark MC, Arditi M, Comin-Anduix B, Ribas A, Lowenstein PR, Castro MG. Curtin JF, et al. PLoS Med. 2009 Jan 13;6(1):e10. doi: 10.1371/journal.pmed.1000010. PLoS Med. 2009. PMID: 19143470 Free PMC article.
Release of HMGB1 in response to proapoptotic glioma killing strategies: efficacy and neurotoxicity.
Candolfi M, Yagiz K, Foulad D, Alzadeh GE, Tesarfreund M, Muhammad AK, Puntel M, Kroeger KM, Liu C, Lee S, Curtin JF, King GD, Lerner J, Sato K, Mineharu Y, Xiong W, Lowenstein PR, Castro MG. Candolfi M, et al. Among authors: curtin jf. Clin Cancer Res. 2009 Jul 1;15(13):4401-14. doi: 10.1158/1078-0432.CCR-09-0155. Clin Cancer Res. 2009. PMID: 19570774 Free PMC article.
A novel bicistronic high-capacity gutless adenovirus vector that drives constitutive expression of herpes simplex virus type 1 thymidine kinase and tet-inducible expression of Flt3L for glioma therapeutics.
Puntel M, Muhammad AK, Candolfi M, Salem A, Yagiz K, Farrokhi C, Kroeger KM, Xiong W, Curtin JF, Liu C, Bondale NS, Lerner J, Pechnick RN, Palmer D, Ng P, Lowenstein PR, Castro MG. Puntel M, et al. Among authors: curtin jf. J Virol. 2010 Jun;84(12):6007-17. doi: 10.1128/JVI.00398-10. Epub 2010 Apr 7. J Virol. 2010. PMID: 20375153 Free PMC article.
Optimization of adenoviral vector-mediated transgene expression in the canine brain in vivo, and in canine glioma cells in vitro.
Candolfi M, Pluhar GE, Kroeger K, Puntel M, Curtin J, Barcia C, Muhammad AK, Xiong W, Liu C, Mondkar S, Kuoy W, Kang T, McNeil EA, Freese AB, Ohlfest JR, Moore P, Palmer D, Ng P, Young JD, Lowenstein PR, Castro MG. Candolfi M, et al. Neuro Oncol. 2007 Jul;9(3):245-58. doi: 10.1215/15228517-2007-012. Epub 2007 May 23. Neuro Oncol. 2007. PMID: 17522335 Free PMC article.
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