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Extensive analysis of the T315I substitution and detection of additional ABL mutations in progenitors and primitive stem cell compartment in a patient with tyrosine kinase inhibitor-resistant chronic myeloid leukemia.
Chomel JC, Sorel N, Bonnet ML, Bertrand A, Brizard F, Roy L, Guilhot F, Turhan AG. Chomel JC, et al. Among authors: turhan ag. Leuk Lymphoma. 2010 Nov;51(11):2103-11. doi: 10.3109/10428194.2010.520774. Epub 2010 Oct 7. Leuk Lymphoma. 2010. PMID: 20929330
The durable clearance of the T315I BCR-ABL mutated clone in chronic phase chronic myelogenous leukemia patients on omacetaxine allows tyrosine kinase inhibitor rechallenge.
Nicolini FE, Chomel JC, Roy L, Legros L, Chabane K, Ducastelle S, Nicolas-Virelizier E, Michallet M, Tigaud I, Magaud JP, Turhan A, Guilhot F, Hayette S. Nicolini FE, et al. Clin Lymphoma Myeloma Leuk. 2010 Oct;10(5):394-9. doi: 10.3816/CLML.2010.n.073. Clin Lymphoma Myeloma Leuk. 2010. PMID: 21030353
164 results