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Structure-activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a novel small molecule hypoxia inducible factor-1 (HIF-1) pathway inhibitor and anti-cancer agent.
Mun J, Jabbar AA, Devi NS, Liu Y, Van Meir EG, Goodman MM. Mun J, et al. Among authors: jabbar aa. Bioorg Med Chem. 2012 Jul 15;20(14):4590-7. doi: 10.1016/j.bmc.2012.04.064. Epub 2012 May 14. Bioorg Med Chem. 2012. PMID: 22682301 Free PMC article.
Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents.
Mun J, Jabbar AA, Devi NS, Yin S, Wang Y, Tan C, Culver D, Snyder JP, Van Meir EG, Goodman MM. Mun J, et al. Among authors: jabbar aa. J Med Chem. 2012 Aug 9;55(15):6738-50. doi: 10.1021/jm300752n. Epub 2012 Jul 24. J Med Chem. 2012. PMID: 22746274 Free PMC article.
Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors.
Tan C, de Noronha RG, Devi NS, Jabbar AA, Kaluz S, Liu Y, Mooring SR, Nicolaou KC, Wang B, Van Meir EG. Tan C, et al. Among authors: jabbar aa. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5528-32. doi: 10.1016/j.bmcl.2011.06.099. Epub 2011 Jun 28. Bioorg Med Chem Lett. 2011. PMID: 21831638 Free PMC article.
Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP.
Yin S, Kaluz S, Devi NS, Jabbar AA, de Noronha RG, Mun J, Zhang Z, Boreddy PR, Wang W, Wang Z, Abbruscato T, Chen Z, Olson JJ, Zhang R, Goodman MM, Nicolaou KC, Van Meir EG. Yin S, et al. Among authors: jabbar aa. Clin Cancer Res. 2012 Dec 15;18(24):6623-33. doi: 10.1158/1078-0432.CCR-12-0861. Epub 2012 Aug 24. Clin Cancer Res. 2012. PMID: 22923450 Free PMC article.
Phytochemical Profiling, Acute Toxicity, and Hepatoprotective Effects of Anchusa Limbata in Thioacetamide-Induced Liver Cirrhosis in Rats.
Abdul-Aziz Ahmed K, Jabbar AAJ, Raouf MMHM, M Al-Qaaneh A, Rizgar Hassan R, Ismael Salih M, Mothana RA, Abdulaziz Al-Hamoud G, Ameen Abdulla M, Hasson S, Abdul-Samad Ismail P. Abdul-Aziz Ahmed K, et al. Among authors: jabbar aaj. Food Sci Nutr. 2024 Nov 21;12(12):10628-10645. doi: 10.1002/fsn3.4544. eCollection 2024 Dec. Food Sci Nutr. 2024. PMID: 39723071 Free PMC article.
Association of BMI, lipid-lowering medication, and age with prevalence of type 2 diabetes in adults with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study.
European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration (EAS FHSC). European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration (EAS FHSC). Lancet Diabetes Endocrinol. 2024 Nov;12(11):811-823. doi: 10.1016/S2213-8587(24)00221-3. Epub 2024 Oct 4. Lancet Diabetes Endocrinol. 2024. PMID: 39374602 Free article.
Uniqueness of lung cancer in Southeast Asia.
Noronha V, Budukh A, Chaturvedi P, Anne S, Punjabi A, Bhaskar M, Sahoo TP, Menon N, Shah M, Batra U, Nathany S, Kumar R, Shetty O, Ghodke TP, Mahajan A, Chakrabarty N, Hait S, Tripathi SC, Chougule A, Chandrani P, Tripathi VK, Jiwnani S, Tibdewal A, Maheshwari G, Kothari R, Patil VM, Bhat RS, Khanderia M, Mahajan V, Prakash R, Sharma S, Jabbar AA, Yadav BK, Uddin AFMK, Dutt A, Prabhash K. Noronha V, et al. Among authors: jabbar aa. Lancet Reg Health Southeast Asia. 2024 Jul 8;27:100430. doi: 10.1016/j.lansea.2024.100430. eCollection 2024 Aug. Lancet Reg Health Southeast Asia. 2024. PMID: 39157507 Free PMC article. Review.
96 results