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Page 1
Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson's disease.
de Freitas Silva M, Juliet Cristancho Ortiz C, Ferreira Coelho L, Pruccoli L, Pagliarani B, Pisani L, Catto M, Poli G, Tuccinardi T, Cardoso Vilela F, Giusti-Paiva A, Amaral Alves M, Ribeiro de Souza HM, Tarozzi A, Silva Gontijo V, Viegas C Jr. de Freitas Silva M, et al. Among authors: viegas c jr. Bioorg Chem. 2024 Sep;150:107587. doi: 10.1016/j.bioorg.2024.107587. Epub 2024 Jun 22. Bioorg Chem. 2024. PMID: 38941700
A synthetic resveratrol-curcumin hybrid derivative exhibits chemopreventive effects on colon pre-neoplastic lesions by targeting Wnt/β-catenin signaling, anti-inflammatory and antioxidant pathways.
Baptistella MM, Assunção RRS, Sales de Oliveira C, Siqueira AP, Gonçalves Dos Santos E, de Freitas Silva M, Lima ETF, Caixeta ES, Novaes RD, Ferreira EB, Ionta M, Viegas C Jr, Francielli de Oliveira P. Baptistella MM, et al. Among authors: viegas c jr. J Pharm Pharmacol. 2024 May 3;76(5):479-488. doi: 10.1093/jpp/rgad077. J Pharm Pharmacol. 2024. PMID: 37874746
Chemical Composition, Anthelmintic Activity, and Mechanism of Action of Lippia dominguensis Mold. Essential Oil on Haemonchus contortus.
Espino Ureña MJ, Katchborian-Neto A, Trinidad AB, Ramírez Ramírez M, Vásquez Tineo M, Vilemar de Araújo-Filho J, Ribeiro WLC, de Souza Collares Maia Castelo-Branco D, de Oliveira LMB, Bevilaqua CML, Chagas-Paula DA, Viegas C Jr, Marques MJ. Espino Ureña MJ, et al. Among authors: viegas c jr. Chem Biodivers. 2023 Jul;20(7):e202300135. doi: 10.1002/cbdv.202300135. Epub 2023 Jun 16. Chem Biodivers. 2023. PMID: 37172262
Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer's disease.
Macedo Vaz S, de Freitas Silva M, Dos Reis Rosa Franco G, Jorge R Guimarães M, Motta R da Silva F, Gonçalves Castro N, Alvim Guedes I, Dardenne LE, Amaral Alves M, Garrett da Costa R, Beserra Pinheiro G, Germino Veras L, Renata Mortari M, Pruccoli L, Tarozzi A, Viegas C Jr. Macedo Vaz S, et al. Among authors: viegas c jr. Bioorg Med Chem. 2022 Oct 1;71:116952. doi: 10.1016/j.bmc.2022.116952. Epub 2022 Aug 1. Bioorg Med Chem. 2022. PMID: 35930852
Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation.
Cristancho Ortiz CJ, de Freitas Silva M, Pruccoli L, Fonseca Nadur N, de Azevedo LL, Kümmerle AE, Guedes IA, Dardenne LE, Leomil Coelho LF, Guimarães MJ, da Silva FMR, Castro N, Gontijo VS, Rojas VCT, de Oliveira MK, Vilela FC, Giusti-Paiva A, Barbosa G, Lima LM, Pinheiro GB, Veras LG, Mortari MR, Tarozzi A, Viegas C Jr. Cristancho Ortiz CJ, et al. Among authors: viegas c jr. RSC Med Chem. 2022 Mar 17;13(5):568-584. doi: 10.1039/d1md00374g. eCollection 2022 May 25. RSC Med Chem. 2022. PMID: 35694691 Free PMC article.
38 results