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Page 1
PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism.
Carnevale D, Vecchione C, Mascio G, Esposito G, Cifelli G, Martinello K, Landolfi A, Selvetella G, Grieco P, Damato A, Franco E, Haase H, Maffei A, Ciraolo E, Fucile S, Frati G, Mazzoni O, Hirsch E, Lembo G. Carnevale D, et al. Among authors: maffei a. Cardiovasc Res. 2012 Jan 1;93(1):200-9. doi: 10.1093/cvr/cvr288. Epub 2011 Oct 27. Cardiovasc Res. 2012. PMID: 22038741
PI3Kγ Inhibition Protects Against Diabetic Cardiomyopathy in Mice.
Maffei A, Cifelli G, Carnevale R, Iacobucci R, Pallante F, Fardella V, Fardella S, Hirsch E, Lembo G, Carnevale D. Maffei A, et al. Rev Esp Cardiol (Engl Ed). 2017 Jan;70(1):16-24. doi: 10.1016/j.rec.2016.04.034. Epub 2016 Jul 13. Rev Esp Cardiol (Engl Ed). 2017. PMID: 27422446 English, Spanish.
Mechanisms of soluble beta-amyloid impairment of endothelial function.
Gentile MT, Vecchione C, Maffei A, Aretini A, Marino G, Poulet R, Capobianco L, Selvetella G, Lembo G. Gentile MT, et al. Among authors: maffei a. J Biol Chem. 2004 Nov 12;279(46):48135-42. doi: 10.1074/jbc.M407358200. Epub 2004 Aug 19. J Biol Chem. 2004. PMID: 15319431 Free article.
Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma.
Vecchione C, Patrucco E, Marino G, Barberis L, Poulet R, Aretini A, Maffei A, Gentile MT, Storto M, Azzolino O, Brancaccio M, Colussi GL, Bettarini U, Altruda F, Silengo L, Tarone G, Wymann MP, Hirsch E, Lembo G. Vecchione C, et al. Among authors: maffei a. J Exp Med. 2005 Apr 18;201(8):1217-28. doi: 10.1084/jem.20040995. Epub 2005 Apr 11. J Exp Med. 2005. PMID: 15824082 Free PMC article.
Selective Rac-1 inhibition protects from diabetes-induced vascular injury.
Vecchione C, Aretini A, Marino G, Bettarini U, Poulet R, Maffei A, Sbroggiò M, Pastore L, Gentile MT, Notte A, Iorio L, Hirsch E, Tarone G, Lembo G. Vecchione C, et al. Among authors: maffei a. Circ Res. 2006 Feb 3;98(2):218-25. doi: 10.1161/01.RES.0000200440.18768.30. Epub 2005 Dec 15. Circ Res. 2006. PMID: 16357302
Resistin impairs insulin-evoked vasodilation.
Gentile MT, Vecchione C, Marino G, Aretini A, Di Pardo A, Antenucci G, Maffei A, Cifelli G, Iorio L, Landolfi A, Frati G, Lembo G. Gentile MT, et al. Among authors: maffei a. Diabetes. 2008 Mar;57(3):577-83. doi: 10.2337/db07-0557. Epub 2007 Dec 7. Diabetes. 2008. PMID: 18065520
Nitric oxide mechanisms of nebivolol.
Maffei A, Lembo G. Maffei A, et al. Ther Adv Cardiovasc Dis. 2009 Aug;3(4):317-27. doi: 10.1177/1753944709104496. Epub 2009 May 14. Ther Adv Cardiovasc Dis. 2009. PMID: 19443516 Free article. Review.
Tumor necrosis factor-alpha mediates hemolysis-induced vasoconstriction and the cerebral vasospasm evoked by subarachnoid hemorrhage.
Vecchione C, Frati A, Di Pardo A, Cifelli G, Carnevale D, Gentile MT, Carangi R, Landolfi A, Carullo P, Bettarini U, Antenucci G, Mascio G, Busceti CL, Notte A, Maffei A, Cantore GP, Lembo G. Vecchione C, et al. Among authors: maffei a. Hypertension. 2009 Jul;54(1):150-6. doi: 10.1161/HYPERTENSIONAHA.108.128124. Epub 2009 May 26. Hypertension. 2009. PMID: 19470883
182 results