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PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism.
Carnevale D, Vecchione C, Mascio G, Esposito G, Cifelli G, Martinello K, Landolfi A, Selvetella G, Grieco P, Damato A, Franco E, Haase H, Maffei A, Ciraolo E, Fucile S, Frati G, Mazzoni O, Hirsch E, Lembo G. Carnevale D, et al. Among authors: vecchione c. Cardiovasc Res. 2012 Jan 1;93(1):200-9. doi: 10.1093/cvr/cvr288. Epub 2011 Oct 27. Cardiovasc Res. 2012. PMID: 22038741
[Insulin and arterial hypertension].
Vecchione C, Lembo G, Trimarco B. Vecchione C, et al. Cardiologia. 1997 Oct;42(10):1045-9. Cardiologia. 1997. PMID: 9534279 Review. Italian. No abstract available.
Systemic hypertension and coronary artery disease: the link.
Lembo G, Morisco C, Lanni F, Barbato E, Vecchione C, Fratta L, Trimarco B. Lembo G, et al. Among authors: vecchione c. Am J Cardiol. 1998 Aug 6;82(3A):2H-7H. doi: 10.1016/s0002-9149(98)00484-6. Am J Cardiol. 1998. PMID: 9719015 Review.
275 results