Franich NR - Search Results

1

Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease.

Hickey MA, Zhu C, Medvedeva V, Franich NR, Levine MS, Chesselet MF. Hickey MA, et al. Among authors: franich nr. Mol Cell Neurosci. 2012 Feb;49(2):149-57. doi: 10.1016/j.mcn.2011.10.007. Epub 2011 Oct 20. Mol Cell Neurosci. 2012. PMID: 22044764 Free PMC article.

2

Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease.

Hickey MA, Zhu C, Medvedeva V, Lerner RP, Patassini S, Franich NR, Maiti P, Frautschy SA, Zeitlin S, Levine MS, Chesselet MF. Hickey MA, et al. Among authors: franich nr. Mol Neurodegener. 2012 Apr 4;7:12. doi: 10.1186/1750-1326-7-12. Mol Neurodegener. 2012. PMID: 22475209 Free PMC article.

3

Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice.

Reidling JC, Relaño-Ginés A, Holley SM, Ochaba J, Moore C, Fury B, Lau A, Tran AH, Yeung S, Salamati D, Zhu C, Hatami A, Cepeda C, Barry JA, Kamdjou T, King A, Coleal-Bergum D, Franich NR, LaFerla FM, Steffan JS, Blurton-Jones M, Meshul CK, Bauer G, Levine MS, Chesselet MF, Thompson LM. Reidling JC, et al. Among authors: franich nr. Stem Cell Reports. 2018 Jan 9;10(1):58-72. doi: 10.1016/j.stemcr.2017.11.005. Epub 2017 Dec 7. Stem Cell Reports. 2018. PMID: 29233555 Free PMC article.

4

Phenotype onset in Huntington's disease knock-in mice is correlated with the incomplete splicing of the mutant huntingtin gene.

Franich NR, Hickey MA, Zhu C, Osborne GF, Ali N, Chu T, Bove NH, Lemesre V, Lerner RP, Zeitlin SO, Howland D, Neueder A, Landles C, Bates GP, Chesselet MF. Franich NR, et al. J Neurosci Res. 2019 Dec;97(12):1590-1605. doi: 10.1002/jnr.24493. Epub 2019 Jul 7. J Neurosci Res. 2019. PMID: 31282030 Free PMC article.

5

Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein.

Subramaniam SR, Vergnes L, Franich NR, Reue K, Chesselet MF. Subramaniam SR, et al. Among authors: franich nr. Neurobiol Dis. 2014 Oct;70:204-13. doi: 10.1016/j.nbd.2014.06.017. Epub 2014 Jul 10. Neurobiol Dis. 2014. PMID: 25016198 Free PMC article.

6

A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-Synuclein.

Richter F, Subramaniam SR, Magen I, Lee P, Hayes J, Attar A, Zhu C, Franich NR, Bove N, De La Rosa K, Kwong J, Klärner FG, Schrader T, Chesselet MF, Bitan G. Richter F, et al. Among authors: franich nr. Neurotherapeutics. 2017 Oct;14(4):1107-1119. doi: 10.1007/s13311-017-0544-9. Neurotherapeutics. 2017. PMID: 28585223 Free PMC article.

7

Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models.

Franich NR, Basso M, André EA, Ochaba J, Kumar A, Thein S, Fote G, Kachemov M, Lau AL, Yeung SY, Osmand A, Zeitlin SO, Ratan RR, Thompson LM, Steffan JS. Franich NR, et al. J Huntingtons Dis. 2018;7(2):137-150. doi: 10.3233/JHD-170274. J Huntingtons Dis. 2018. PMID: 29843246 Free PMC article.

8

AAV vector-mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington's disease.

Franich NR, Fitzsimons HL, Fong DM, Klugmann M, During MJ, Young D. Franich NR, et al. Mol Ther. 2008 May;16(5):947-56. doi: 10.1038/mt.2008.50. Epub 2008 Mar 25. Mol Ther. 2008. PMID: 18388917 Free PMC article.

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